NH 2-modified upconverting nanoparticles(hyacinthine light), 20 mgProduct Type: Upconverting nanoparticle
Research-grade laboratory product
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LABORATORY PROCUREMENT SUPPORT
For model selection, material format, solvent, concentration or configuration confirmation, contact our technical sales team.
E-MAIL: inquiry@atomfair.com
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Manufacturer: Atomfair LLC
Brand: ATOMFAIR®
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Manufacturer: Atomfair LLC
Brand: ATOMFAIR®
How does the 35 nm particle size of NH2-modified upconverting nanoparticles affect the dual emission at 365 nm and 475 nm for biological imaging applications?
The 35 nm particle size balances surface area for NH2 bioconjugation with upconversion efficiency. The dual emission peaks at 365 nm (UV) and 475 nm (blue) enable multiplexed detection, but smaller particles may reduce quantum yield. The provided water dispersion is suitable for biological assays, though researchers should confirm colloidal stability in physiological buffers.
Are NH2-modified upconverting nanoparticles compatible with standard biological conjugation protocols for targeting antibodies or DNA?
Yes, the NH2 surface modification allows direct covalent conjugation to carboxylated or NHS-activated biomolecules. The 20 mg package size is supplied in water, facilitating dilution into common buffers like PBS. However, crosslinking or aggregation may occur if pH or ionic strength is not controlled; pre-testing in the intended buffer system is recommended.
What storage and handling conditions are required to preserve the luminescence stability of NH2-modified upconverting nanoparticles?
Store the water dispersion at 2–8°C in the dark to prevent photodegradation of the upconversion luminescence. Avoid freeze-thaw cycles, as they can cause particle aggregation. The NH2 groups are reactive; use the product within 6 months of receipt and handle under inert atmosphere if prolonged air exposure is expected.
This NH2-modified upconverting nanoparticle (NaYREF4) with dual emission at 365/475 nm and 35 nm particle size in water is suitable for fluorescence-based biological detection and imaging applications requiring ratiometric readout.
Positive
- Dual emission peaks enable ratiometric sensing: Two distinct emission wavelengths at 365 nm and 475 nm allow ratiometric fluorescence measurements for improved accuracy in biological detection and imaging.
- Water-dispersible formulation: Solvent is water (as specified), enabling direct use in aqueous biological assays without organic solvent removal steps.
Trade-offs
- Pre-quotation parameter verification required: Concentration, solvent, emission color and package size must be confirmed before ordering due to potential batch-to-batch variation in these parameters.
- Format-dependent preparation workflow: The product may be supplied as powder or dispersion; users must match the received format to their intended preparation protocol and storage conditions as noted in selection guidelines.
Every advanced material, component, equipment, and instrument in our catalog is backed by rigorous testing. We maintain strict internal quality management frameworks and align with CE conformity metrics to deliver transparent, reproducible performance data via our public open-science repository.
To request raw batch performance data, submit formal vendor registration paperwork, or execute a fast-turnaround R&D manufacturing loop, contact us at inquiry@atomfair.com.
Item is dispatched under the Atomfair Shipping & Delivery Framework (Free worldwide shipping on orders over $59 USD excl. heavy equipment). Return is governed by the Atomfair Return & Refund Policy (7-day technical return window).
