Description
MIL-101(Al) Technical Datasheet
Key Properties & Advantages
MIL-101(Al)’s performance stems from its aluminum-based structure and engineered porosity:
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Low Toxicity & Biocompatibility: Aluminum’s inherent low toxicity (compared to heavy metals like Cr or Fe) makes it suitable for biomedical applications, including drug delivery and protein encapsulation, where biocompatibility is critical.
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Exceptional Stability: Maintains structural integrity in aqueous solutions (pH 3–11), organic solvents, and moderate temperatures (up to 300°C), ensuring durability in both biological and industrial environments.
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Large Mesoporous Cavities: Features spacious cavities (~2.9 nm and ~3.4 nm) and a hierarchical pore network, enabling adsorption and encapsulation of large molecules—including proteins, enzymes, and therapeutic agents— MOF
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High Surface Area: Typically exhibits a BET surface area of 1500–2500 m²/g, providing abundant active sites for adsorption, catalytic reactions, and functionalization.
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Low Density: Lightweight structure facilitates easy integration into composite materials (e.g., membranes, hydrogels) without compromising mechanical performance.
Core Applications
Catalysis
MIL-101(Al)’s porous structure and aluminum-based active sites make it an ideal catalyst or catalyst support:
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Heterogeneous Catalysis: Aluminum clusters act as Lewis acid sites, promoting reactions like esterification, alkylation, and CO₂ fixation with high selectivity.
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Enzyme Immobilization: Its large cavities can encapsulate enzymes (e.g., lipases, proteases), stabilizing them for biocatalytic reactions while enabling recyclability—critical for sustainable industrial processes.
Targeted Pollutant Adsorption & Removal
Its high surface area and mesoporous cavities enable efficient capture of diverse contaminants:
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Organic Pollutant Removal: Adsorbs large organic molecules (e.g., dyes, pesticides, pharmaceuticals) from water via pore confinement and hydrophobic interactions, achieving high removal efficiencies even at low concentrations.
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Heavy Metal Ion Capture: Aluminum sites chelate with toxic metal ions (e.g., Pb²⁺, Cd²⁺) via electrostatic interactions, supporting wastewater purification in environmental remediation.
Drug Delivery Systems
MIL-101(Al)’s biocompatibility and large pores position it as a promising platform for controlled drug release:
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Protein & Biomolecule Encapsulation: Spacious cavities can encapsulate large biomolecules (e.g., antibodies, growth factors) and therapeutic proteins, protecting them from degradation while enabling targeted delivery.
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Controlled Drug Release: Tunable porosity and surface chemistry allow for pH-responsive or stimuli-triggered release of encapsulated drugs (e.g., anticancer agents), improving therapeutic efficacy and reducing side effects.
Technical Specifications
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Parameter
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Details
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Chemical Composition
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Aluminum(III) clusters linked by terephthalate ligands (Al₃O(OH)(bdc)₃, where bdc = 1,4-benzenedicarboxylate)
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Appearance
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White to off-white crystalline powder
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BET Surface Area
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1500–2500 m²/g
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Pore Size
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Large mesoporous cavities (~2.9 nm and ~3.4 nm)
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Thermal Stability
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Up to 300°C (inert atmosphere)
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pH Stability
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3–11 (aqueous solutions)
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Toxicity
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Low; biocompatible for biomedical applications
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Quality Assurance
MIL-101(Al) undergoes rigorous testing to ensure consistency:
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X-ray diffraction (XRD) confirms structural integrity and phase purity.
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Nitrogen adsorption-desorption analysis verifies surface area and pore size distribution.
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Stability testing in aqueous and organic environments ensures performance reliability.
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Biocompatibility assessments (for biomedical grades) confirm low cytotoxicity.
A certificate of analysis (CoA) is provided with each order, documenting batch-specific properties.
Packaging & Storage
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Available in 1g, 5g, 10g, and bulk quantities, packaged in airtight, moisture-resistant containers to preserve porosity. Store at room temperature in a dry environment. Shelf life is ≥12 months under proper storage conditions.
Why Choose MIL-101(Al)?
MIL-101(Al) bridges porous functionality and biocompatibility, making it indispensable for:
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Catalysis and enzyme immobilization (industrial scale).
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Targeted pollutant removal from water and air.
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Drug delivery and biomolecule encapsulation (biomedical research).
Its low toxicity, stability, and large pores make it a versatile choice for applications where both performance and safety are critical.
Contact our technical team for bulk pricing, custom functionalization, or application-specific data.
For research and industrial use. Biomedical applications require further biocompatibility validation.
