Description
HC110-Pro Heating Cooling Dry BathProduct Type: Temperature control instrument
Research-grade temperature control platform
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TAILORED SOLUTIONS FOR RESEARCH
For bulk orders, OEM requirements, accessory matching or configuration confirmation, contact our engineering sales team.
EMAIL: inquiry@atomfair.com
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Supplier: Atomfair
Brand: ATOMFAIR®
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Ambient temperature must be maintained between 10 and 40 °C with relative humidity below 80% to ensure stable operation. The instrument requires a 110/220 V, 50/60 Hz power supply and must be placed on a level surface with adequate ventilation for heat dissipation.
- Temperature Range Limitation: The temperature control range is limited to room temperature minus 25 °C down to 110 °C, with a setting range from -5 to 110 °C, requiring ambient conditions to achieve sub-ambient setpoints.
- Cooling Rate Dependency: Maximum cooling rate decreases from 2.5 °C/min above room temperature to 0.5 °C/min when cooling below room temperature, imposing longer equilibration times for low-temperature protocols.
- Block Compatibility Requirement: Only compatible heating blocks, modules, or sample vessels specifically designed for the HC110-Pro format must be used to ensure proper thermal contact and avoid instrument damage.
This procedure covers initial setup, program configuration, and safe operation of the dry bath for controlled heating and cooling applications. Follow these steps to ensure accurate temperature control and prevent thermal shock to samples or the instrument.
Required Equipment: Compatible heating block or sample module, Sample tubes, vials, or plates
- Install compatible block
Insert the appropriate heating block or sample module into the dry bath well, ensuring it is fully seated and aligned with the thermal interface. - Power on and set temperature
Connect the instrument to a grounded 110/220 V power supply, turn on the main switch, and use the TFT interface to set the desired target temperature within the -5 to 110 °C range. - Configure timer or program
Set the timer from 0 min to 99 h 59 min or load one of the 9 custom programs via the TFT menu to define incubation duration and temperature ramps. - Load samples and start run
Place prepared sample tubes or plates into the block wells, close any lid if present, and press start to initiate the heating or cooling cycle. - Monitor and retrieve samples
Observe the TFT display for real-time temperature and remaining time, then remove samples promptly after the cycle completes to avoid unintended thermal drift.
Why is the cooling rate from room temperature to sub-ambient ten times slower than from 100°C to room temperature on the HC110-Pro dry bath, and how does this affect experimental throughput for applications requiring rapid cooling below ambient?
The maximum cooling rate from 100°C to room temperature is 2.5°C/min, whereas from room temperature to below room temperature it is only 0.5°C/min. This difference means that achieving a target temperature well below ambient can take significantly longer. For workflows such as rapid thermal cycling or enzyme quench steps that demand fast sub-ambient cooling, the slower rate in that regime may limit throughput and should be factored into protocol timing.
Does the HC110-Pro come with a heating/cooling block, or is it required to purchase a separate block compatible with specific tube or plate formats, and how do I identify which Atomfair modular block fits the HC110-Pro?
The HC110-Pro is sold as a base temperature control unit without a block or sample module included. The product description explicitly states to confirm compatible heating blocks, modules, or sample vessels before ordering. For block matching—whether for tubes, vials, plates, or custom formats—contact the Atomfair technical sales team at inquiry@atomfair.com, as they can provide the specific modular block options designed to interface with the HC110-Pro's 200 x 235 x 120 mm footprint.
Can the HC110-Pro be operated in a cold room (4°C) or in a high-humidity environment above 80% RH, and what are the risks if operated outside the specified ambient conditions?
The specified ambient operating range is 10 to 40°C with relative humidity below 80%. Running the unit at 4°C (a typical cold room temperature) or above 80% RH exceeds these limits. Operating outside the specified range risks internal condensation, inaccurate temperature control (since the unit relies on ambient air for heat exchange), potential electronic damage, and voided warranty. If cold-room use is required, consult Atomfair for guidance on derating or protective measures.
The HC110-Pro Heating Cooling Dry Bath provides precise block-based temperature control from RT-25 to 110°C with ±0.5°C accuracy and programmable timers, suitable for enzyme reactions and nucleic acid workflows. However, its cooling performance below ambient is limited to 0.5°C/min and requires a controlled lab environment.
Positive
- Wide temperature range with active cooling: Covers RT-25 to 110°C, enabling both heating and controlled cooling below ambient for enzyme reactions, nucleic acid workflows, and protein handling.
- Programmable multi-step protocols: Supports 9 custom programs and 150 process executions, allowing automated, repeatable incubation sequences without manual intervention.
Trade-offs
- Slow cooling rate below ambient: Maximum cooling rate from room temperature to below room temperature is only 0.5°C/min, limiting rapid temperature transitions for time-sensitive protocols.
- Ambient temperature and humidity constraints: Requires a controlled environment of 10–40°C and <80% relative humidity to maintain specified performance and equipment reliability.
Every advanced material, component, equipment, and instrument in our catalog is backed by rigorous testing. We maintain strict internal quality management frameworks and align with CE conformity metrics to deliver transparent, reproducible performance data via our public open-science repository.
To request raw batch performance data, submit formal vendor registration paperwork, or execute a fast-turnaround R&D manufacturing loop, contact us at inquiry@atomfair.com.
Item is dispatched under the Atomfair Shipping & Delivery Framework (Free worldwide shipping on orders over $59 USD). Return is governed by the Atomfair Return & Refund Policy (7-day technical return window).





