Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair Bis(trimethylsilyl) oxalate C8H18O4Si2 CAS 18294-04-7

Bis(trimethylsilyl) oxalate (CAS 18294-04-7) is a high-purity silylating reagent with the molecular formula C8H18O4Si2. This compound is widely utilized in organic synthesis and pharmaceutical research as a protective agent for hydroxyl and carboxyl groups. Its unique trimethylsilyl (TMS) groups enhance reactivity and solubility in non-polar solvents, making it ideal for derivatization in GC-MS analysis. Supplied as a clear, colorless liquid, it is moisture-sensitive and should be stored under inert conditions. Each batch undergoes rigorous QC testing including NMR, HPLC, and GC to ensure ≥98% purity, meeting the stringent demands of research and industrial applications.

Category:

Description

Bis(trimethylsilyl) oxalate (CAS 18294-04-7) is a high-purity silylating reagent with the molecular formula C8H18O4Si2. This compound is widely utilized in organic synthesis and pharmaceutical research as a protective agent for hydroxyl and carboxyl groups. Its unique trimethylsilyl (TMS) groups enhance reactivity and solubility in non-polar solvents, making it ideal for derivatization in GC-MS analysis. Supplied as a clear, colorless liquid, it is moisture-sensitive and should be stored under inert conditions. Each batch undergoes rigorous QC testing including NMR, HPLC, and GC to ensure ≥98% purity, meeting the stringent demands of research and industrial applications.

Properties

  • CAS Number: 18294-04-7
  • Complexity: 211
  • IUPAC Name: bis(trimethylsilyl) oxalate
  • InChI: InChI=1S/C8H18O4Si2/c1-13(2,3)11-7(9)8(10)12-14(4,5)6/h1-6H3
  • InChI Key: DDCDOSJHFOGNRO-UHFFFAOYSA-N
  • Exact Mass: 234.07436212
  • Molecular Formula: C8H18O4Si2
  • Molecular Weight: 234.40
  • SMILES: C[Si](C)(C)OC(=O)C(=O)O[Si](C)(C)C
  • Topological: 52.6
  • Monoisotopic Mass: 234.07436212
  • Synonyms: Bis(trimethylsilyl) oxalate, 18294-04-7, Oxalic acid, bis(trimethylsilyl) ester, ETHANEDIOICACID,BIS(TRIMETHYLSILY, Ethanedioic acid, bis(trimethylsilyl) ester, Oxalic acid, diTMS, Oxalic acid (2TMS), Oxalic acid, bis-TMS, Oxalic acid, bis-TMS ester, Oxalic acid, 2TMS derivative, SCHEMBL1055321, DDCDOSJHFOGNRO-UHFFFAOYSA-N, DTXSID101337463, oxalyl acid bis(trimethylsilylester), Oxalic acid, bistrimethylsilyl ester, ethanedioic acid bis(trimethylsilyl) ester

Application

Bis(trimethylsilyl) oxalate is primarily used as a derivatization agent in gas chromatography-mass spectrometry (GC-MS) for the analysis of polar compounds. It serves as a protecting group for carboxylic acids and alcohols in complex organic syntheses, particularly in peptide and carbohydrate chemistry. The compound also finds utility in the preparation of silicon-based polymers and as a precursor for specialty chemicals in material science.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products