UIO-66 High-Stability MOF Powder CAS: 1072413-89-8 | Zirconium-Based Metal-Organic Framework | KAR-F30

Key Properties & Advantages

• Exceptional Stability: Outperforms most MOFs in chemical and thermal resilience—withstands temperatures up to 400°C (under inert conditions), resists degradation in acids (pH ≥ 2), bases (pH ≤ 12), and organic solvents, and maintains integrity in aqueous environments. This stability ensures longevity in practical applications where other MOFs fail.
• Tunable Framework: Its flexible structure supports diverse modification strategies:
  • Doping: Incorporation of metal ions (e.g., Fe, Cu, Ti) into zirconium clusters to introduce catalytic or photocatalytic activity.
  • Post-Synthetic Modification: Functional groups (e.g., -NH₂, -OH, -COOH) can be grafted onto ligands to enhance selectivity in adsorption, coordination, or biocompatibility.
  • Pore Engineering: Adjustment of ligand length or linker chemistry to tailor pore size (typically 0.8–1.2 nm) and surface area (BET 1000–1500 m²/g) for target molecules.
• High Coordination Capability: Zirconium clusters offer abundant coordination sites, enabling strong interactions with guest molecules, metal nanoparticles, or biomolecules—critical for catalysis, sensing, and drug delivery.
• Structural Integrity: Retains its ordered porous network even after modification, ensuring consistent performance in applications requiring mass transport (e.g., adsorption, catalysis).

Modification Strategies

• Doping: Introduction of heteroatoms (e.g., Hf, Ce) or metal ions (e.g., Ru, Co) into the zirconium clusters to modify electronic properties, enhance catalytic activity, or enable photocatalytic responses (e.g., light-driven water splitting).
• Post-Synthetic Modification (PSM): Chemical functionalization of ligands after synthesis, such as:
  • Grafting amine (-NH₂), hydroxyl (-OH), or carboxyl (-COOH) groups to improve hydrophilicity or selectivity for polar molecules.
  • Covalent linking of biomolecules (e.g., peptides, antibodies) for targeted biomedical applications.
• Ligand Exchange: Partial or full replacement of terephthalate ligands with functionalized linkers (e.g., fluorinated, sulfonated) to adjust porosity, surface chemistry, or reactivity.

Applications Across Fields

Catalysis & Photocatalysis

• Heterogeneous Catalysis: Serves as a stable support for metal nanoparticles (e.g., Pd, Pt) or as an intrinsic catalyst via zirconium’s Lewis acidity, enabling reactions like hydrogenation, oxidation, and CO₂ conversion.
• Photocatalysis: Modified UiO-66 (e.g., with Ti doping or dye sensitization) drives light-induced reactions such as water splitting for H₂ production, pollutant degradation, and CO₂ photoreduction to fuels.

Adsorption & Separation

• Gas Separation: Tuned pores and functional groups enable selective adsorption of gases (e.g., CO₂/N₂, H₂/CH₄), supporting carbon capture, natural gas purification, and hydrogen storage.
• Liquid-Phase Adsorption: Removes pollutants (e.g., heavy metals, dyes, pharmaceuticals) from water via ligand-metal interactions or hydrophobic/hydrophilic effects, depending on modifications.

Sensing

• Molecular Sensing: Functionalized UiO-66 (e.g., with fluorescent groups or metal ions) detects target analytes (e.g., heavy metals, volatile organic compounds, biomolecules) via changes in luminescence, conductivity, or adsorption behavior.
• Environmental Sensing: Its stability in aqueous media makes it suitable for real-time monitoring of water or air quality.

Biomedical Applications

• Drug Delivery: Biocompatible zirconium framework and porous structure enable controlled encapsulation and release of drugs, with modifications (e.g., -NH₂ groups) enhancing targeting to specific tissues.
• Imaging: Doped UiO-66 (e.g., with rare-earth ions) acts as a contrast agent for magnetic resonance imaging (MRI) or fluorescence imaging, leveraging its stability in biological environments.

Technical Specifications

Quality Assurance

• X-ray diffraction (XRD) to confirm phase purity and crystallinity.
• Nitrogen adsorption-desorption analysis to verify surface area and pore size distribution.
• Thermal gravimetric analysis (TGA) to validate thermal stability.
• Stability testing in relevant solvents and pH conditions for application-specific reliability.

Packaging & Storage

• Available in 1g, 5g, 10g, and bulk quantities, packaged in airtight, moisture-resistant containers to preserve porosity and stability. Store at room temperature in a dry environment. Shelf life is ≥12 months under proper storage conditions.

Why Choose UiO-66?