For protein folding intermediates during chaperone-mediated amyloid prevention
protein misfolding
molecular chaperones
amyloidosis
structural biology
neurodegenerative diseases
Exploring the role of stem cell exhaustion reversal in aging-related neurodegenerative diseases
stem cells
neurodegeneration
aging
cellular rejuvenation
Alzheimer's disease
Targeting prion disease reversal through synthetic protein scaffolds
prion disease
synthetic biology
protein engineering
neurodegenerative disorders
therapeutic scaffolds
Engineering viral vectors with CRISPR-Cas12a for targeted gene delivery in neurodegenerative diseases
viral vectors
CRISPR-Cas12a
gene therapy
neurodegenerative diseases
targeted delivery
Targeting protein misfolding with CRISPR-based therapies for neurodegenerative diseases
protein misfolding
CRISPR
neurodegenerative diseases
gene therapy
Alzheimer's
Investigating synaptic vesicle recycling dynamics using super-resolution microscopy in neurodegenerative models
synaptic vesicles
super-resolution microscopy
neurodegeneration
Alzheimer's
presynaptic terminals
Targeting protein misfolding with senolytic drug discovery for age-related neurodegenerative diseases
protein misfolding
senolytics
neurodegeneration
drug discovery
aging
Targeting protein misfolding with AI-driven molecular chaperone design
protein misfolding
molecular chaperones
AI drug design
neurodegeneration
amyloidosis
Mitigating neurodegenerative diseases through targeted inflammasome inhibition in microglia
neuroinflammation
NLRP3 inflammasome
microglia
Alzheimer’s disease
drug discovery
Targeting protein misfolding with CRISPR-engineered chaperones for neurodegenerative disease therapy
protein misfolding
CRISPR chaperones
neurodegenerative diseases
therapeutic engineering
molecular correction
With epigenetic reprogramming to reverse age-related cognitive decline in primates
epigenetic reprogramming
cognitive decline
aging reversal
primate models
gene therapy
Using plasma membrane repair mechanisms to combat neurodegenerative protein aggregation
membrane repair
neurodegeneration
protein aggregation
lipid bilayers
therapeutic targets