Modulating the proteostasis network to reverse age-related protein aggregation
proteostasis
protein aggregation
neurodegeneration
aging
chaperone proteins
Targeting prion disease reversal with CRISPR-based protein disaggregation
prion diseases
CRISPR-Cas9
protein disaggregation
neurodegeneration
gene editing
Targeting protein misfolding in neurodegenerative diseases using AI-driven molecular docking
protein misfolding
neurodegenerative diseases
AI molecular docking
amyloid-beta
tauopathy
Through proteostasis network modulation in neurodegenerative disease therapy
proteostasis
neurodegeneration
protein aggregation
chaperone systems
therapeutic targets
Optimizing CRISPR-Cas12a gene editing for neurodegenerative disease therapies
CRISPR-Cas12a
neurodegenerative diseases
gene therapy
off-target effects
neuronal cells
Through proteostasis network modulation to delay neurodegenerative disease onset
proteostasis
neurodegeneration
protein aggregation
therapeutic targets
aging
Optimizing viral vector engineering for targeted gene delivery in neurodegenerative diseases
viral vectors
gene therapy
neurodegenerative diseases
capsid engineering
blood-brain barrier
Targeting protein misfolding in neurodegenerative diseases with AI-driven molecular chaperones
protein folding
molecular chaperones
neurodegenerative disorders
computational biology
drug design
In gut-brain axis modulation using engineered probiotics for Parkinson’s disease
gut-brain axis
Parkinson’s disease
engineered probiotics
neuroinflammation
microbiome therapy
Optimizing CRISPR-Cas12a gene editing for neurodegenerative disease therapy in non-dividing cells
CRISPR-Cas12a
neurodegenerative diseases
non-dividing cells
gene therapy
neuronal repair
Controlling proteostasis network modulation within attosecond timeframes to prevent amyloid aggregation
proteostasis
attosecond biology
amyloidosis
protein aggregation
neurodegeneration
Targeting proteostasis network modulation via selective Hsp70 co-chaperone inhibition for neurodegenerative diseases
proteostasis
Hsp70 inhibitors
protein misfolding
neurodegeneration
co-chaperones