Description

Uridine Triacetate (CAS No. 4105-38-8) is a high-purity, acetylated derivative of uridine with the molecular formula C₁₅H₁₈N₂O₉. This compound, also known as 2′,3′,5′-Tri-O-acetyluridine or Triacetyluridine, is a white to off-white crystalline powder with excellent stability and solubility in organic solvents. Its IUPAC name is [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate. Uridine Triacetate is widely utilized in pharmaceutical research, nucleotide synthesis, and as a prodrug for uridine supplementation. Our product is rigorously tested for purity (≥98% by HPLC) and is supplied in sealed, light-resistant packaging to ensure long-term stability. Ideal for researchers studying nucleoside metabolism, drug delivery systems, and enzyme inhibition.

Properties

• CAS Number: 4105-38-8
• Complexity: 660
• IUPAC Name: [(2R,3R,4R,5R)-3,4-diacetoxy-5-(2,4-dioxopyrimidin-1-yl)tetrahydrofuran-2-yl]methyl acetate
• InChI: InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1
• InChI Key: AUFUWRKPQLGTGF-FMKGYKFTSA-N
• Exact Mass: 370.10123016
• Molecular Formula: C15H18N2O9
• Molecular Weight: 370.31
• SMILES: CC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=O)NC2=O)OC(=O)C)OC(=O)C
• Topological: 138
• Monoisotopic Mass: 370.10123016
• Synonyms: 4105-38-8, Uridine triacetate, 2′,3′,5′-Tri-O-acetyluridine, Triacetyluridine, Vistonuridine, Xuriden, PN401, 2′,3′,5′-Triacetyluridine, Tri-O-acetyluridine, Vistogard, Uridine 2′,3′,5′-triacetate, Vistogard (TN), PN 401, PN-401, RG2133, Xuriden (TN), Triacetate d’uridine, RG 2133, RG-2133, Triacetato de uridina, Uridine triacetate [USAN:INN], 2WP61F175M, EINECS 223-881-5, URIDINE TRIACETATE [MI], URIDINE TRIACETATE [INN], CHEBI:90914, URIDINE TRIACETATE [USAN], DTXSID40961409, URIDINE TRIACETATE [WHO-DD], URIDINE TRIACETATE [ORANGE BOOK], NSC79269, [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl acetate, uridini triacetas, ((2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl)methyl acetate, A16AX13, DTXCID001380019, 223-881-5, triacetyl uridine, (2R,3R,4R,5R)-2-(ACETOXYMETHYL)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-3,4-DIYL DIACETATE, MFCD00023795, [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate, UNII-2WP61F175M, Uridinetriacetate, uridine-triacetate, C15H18N2O9, Uridine, 2,3,5-triacetate, MLS006009982, SCHEMBL871011, CHEMBL2107381, Uridine triacetate (USAN/INN), [(2R,3R,4R,5S)-3,4-Diacetyloxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate, CS-D1799, NSC788948, s6484, AKOS015964563, DB09144, NSC-788948, NT06907, HY-14905, SMR004701034, SY004945, 2′,3′,5′-Tri-O-acetyluridine, >=98%, 2a(2),3a(2),5a(2)-Tri-O-acetyluridine, NS00047457, D09985, EN300-7359679, BRD-K18323388-001-01-1, Q22075857, Uridine 2′,3′,5′-triacetate;2′,3′,5′-Tri-O-acetyl-D-uridine, 2 inverted exclamation mark ,3 inverted exclamation mark ,5 inverted exclamation mark -Triacetyluridine

Application

Uridine Triacetate is primarily used as a prodrug to increase uridine bioavailability in therapeutic applications, particularly in mitigating toxicity from chemotherapy agents like 5-fluorouracil. It serves as a key intermediate in nucleotide synthesis and is employed in biochemical studies of pyrimidine metabolism. Researchers also explore its potential in neuroprotection and mitochondrial function enhancement due to its role in RNA synthesis and cellular energy pathways.

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