Description

Uracil (CAS: 66-22-8) is a naturally occurring pyrimidine nucleobase with the molecular formula C₄H₄N₂O₂. It is a fundamental component of RNA, where it pairs with adenine via hydrogen bonds. This high-purity compound is essential for biochemical research, pharmaceutical development, and molecular biology applications. Our Uracil is rigorously tested to ensure ≥99% purity, making it suitable for cell culture, enzymatic studies, and as a reference standard in analytical chemistry. Available in various quantities, this product is ideal for researchers requiring reliable and consistent quality for their experiments.

Key Features:

• High Purity: ≥99% (HPLC)
• Molecular Weight: 112.09 g/mol
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in water (1 mg/mL) and dilute acids
• Storage: Store at 2-8°C in a dry environment
• Applications: Nucleic acid research, drug synthesis, and diagnostic reagent preparation

This product complies with USP, EP, and BioReagent standards, ensuring versatility across research and industrial applications.

Properties

• CAS Number: 66-22-8
• Complexity: 161
• IUPAC Name: 1H-pyrimidine-2,4-dione
• InChI: InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
• InChI Key: ISAKRJDGNUQOIC-UHFFFAOYSA-N
• Exact Mass: 112.027277375
• Molecular Formula: C4H4N2O2
• Molecular Weight: 112.09
• SMILES: C1=CNC(=O)NC1=O
• Topological: 58.2
• Monoisotopic Mass: 112.027277375
• Physical Description: Solid; White powder;
• Dissociation Constants: 9.45
• Synonyms: uracil, 66-22-8, 2,4-Dihydroxypyrimidine, pyrimidine-2,4(1H,3H)-dione, Pyrod, 2,4-Dioxopyrimidine, Hybar X, 2,4-Pyrimidinedione, Pirod, RU 12709, Urazil, Ura, CCRIS 3077, CHEBI:17568, NSC 3970, NSC-3970, AI3-25470, SQ-6201, SQ-7726, SQ-8493, BMS-205603-01, UNII-56HH86ZVCT, EINECS 200-621-9, 56HH86ZVCT, DTXSID4021424, NSC3970, DTXCID101424, URACIL (USP-RS), URACIL [USP-RS], URACIL (MART.), URACIL [MART.], LAMIVUDINE IMPURITY F (EP IMPURITY), LAMIVUDINE IMPURITY F [EP IMPURITY], FLUOROURACIL IMPURITY C (EP IMPURITY), FLUOROURACIL IMPURITY C [EP IMPURITY], LAMIVUDINE IMPURITY E (USP IMPURITY), LAMIVUDINE IMPURITY E [USP IMPURITY], FLUOROURACIL SPECIFIED COMPOUND C (USP IMPURITY), FLUOROURACIL SPECIFIED COMPOUND C [USP IMPURITY], 2, 4-Dioxopyrimidine, 2-hydroxy-4-(1H)-pyrimidione, 2-hydroxy-4-(3H)-pyrimidione, 4-hydroxy-2-(1H)-pyrimidione, 200-621-9, 2,4(1H,3H)-Pyrimidinedione, pyrimidine-2,4-diol, 2,4-Pyrimidinediol, 51953-14-1, 1H-Pyrimidine-2,4-dione, 1,2,3,4-tetrahydropyrimidine-2,4-dione, Uracil [USAN], MFCD00006016, 2,4-Pyrimidinediol (9CI), Uracyl, 2-Hydroxy-4(3H)-pyrimidinone, SQ 6201, SQ 7726, SQ 8493, BMS 205603-01, Lamivudine impurity e, 2-Hydroxy-4(1H)-pyrimidinone, 66255-05-8, Lamivudine impurity e rs, 144104-68-7, 4-Hydroxy-2(1H)-pyrimidinone, Fluorouracil specified compound c, NCGC00181030-01, 4-Hydroxyuracil, CAS-66-22-8, CID 5274267, Pyrimidine-2,4(1H,3H)-dione (Uracil), Uracil (8CI), Uracil [USAN:JAN], 2(1H)-Pyrimidinone, 4-hydroxy-, 2(1H)-Pyrimidinone, 6-hydroxy-, 4(3H)-Pyrimidinone, 2-hydroxy-, 66224-60-0, 8h-uracil, hydroxypyrimidinone, Uracil (Standard), 2,6-Dioxypyrimidin, 2,4-Dioxypyrimidine, 2,4(1H,3H)-Pyrimidinedione (9CI), pyrimidine-2,4-dione, Fluorouracil Impurity C, Uracil, 99%, 1ui0, Uracil (JAN/USAN), 2,3H)-Pyrimidinedione, 2,6-Dihydroxypyrimidine, URACIL [JAN], URACIL [WHO-DD], URACIL [MI], bmse000187, bmse000940, CHEMBL566, Epitope ID:120356, NCIMech_000782, SCHEMBL8235, Uracil, >=99.0%, pyrimidine, 2,4-dihydroxy-, SCHEMBL29730, SCHEMBL80962, SCHEMBL94310, 51953-19-6, MLS001304993, SCHEMBL144010, SCHEMBL151239, SCHEMBL537174, SCHEMBL877869, SCHEMBL925137, GTPL4560, SCHEMBL1050479, SCHEMBL5089507, SCHEMBL6286831, SCHEMBL6434097, SCHEMBL6434098, SCHEMBL7267501, SCHEMBL7335265, SCHEMBL9734266, SCHEMBL9779787, 2,4-(1h,3h)-pyrimidinedione, SCHEMBL10580164, SCHEMBL11607890, SCHEMBL13276278, HY-I0960R, Uracil, >=99.0% (T), 1,3-dihydropyrimidine-2,4-dione, DTXSID501007260, HMS2234E19, HMS3264C13, HMS3373E18, HMS3652N05, HMS5082D06, Pharmakon1600-01502345, (4-Hydroxypyrimidin-2-yl)oxidanyl, 4(1H)-Pyrimidinone, 2-hydroxy-, BCP26546, HY-I0960, NSC29742, ZAA89752, Tox21_112680, Tox21_201023, BDBM50549809, CCG-35866, MSK000882, NSC-29742, NSC759649, s4177, SBB058492, STK301734, STL124066, AKOS000119989, AKOS002303991, Tox21_112680_1, 4(3H)-Pyrimidinone,2-hydroxy-(9ci), CCG-213042, CS-W020104, DB03419, FU01843, NSC-759649, PS-5279, SB55489, SB55884, NCGC00181030-02, NCGC00247663-01, NCGC00258576-01, Uracil, Vetec(TM) reagent grade, 98%, NCI60_003718, SMR000752912, SY008943, DB-030518, DB-103964, DB-268940, DB-268966, DB-272084, DB-272202, NS00002070, ST45061548, SW220239-1, U0013, EN300-17138, Uracil, suitable for cell culture, BioReagent, C00106, D00027, SBI-0053640.0002, AB00171810_03, AB00171810_04, AB00918623-05, AC-907/30002021, Q182990, BRD-K80129304-001-08-1, BRD-K80129304-001-09-9, Z56889474, F1796-0008, E2FC11E5-1887-46DF-B415-82313CE9B2BD, Uracil, United States Pharmacopeia (USP) Reference Standard, 2,4(1H,3H)-Pyrimidinedione;2,4-Dihydroxypyrimidine;2,4-Pyrimidinediol, Fluorouracil impurity C, European Pharmacopoeia (EP) Reference Standard, InChI=1/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8, Uracil, Pharmaceutical Secondary Standard; Certified Reference Material

Uracil is widely used as a key intermediate in nucleic acid synthesis and as a precursor for antiviral and anticancer drugs like 5-fluorouracil. It serves as a critical component in RNA studies, including transcription and translation experiments. Researchers also utilize Uracil in metabolic pathway analysis and as a building block for modified nucleosides. Its high purity makes it suitable for cell culture media supplementation and diagnostic assay development.

Safety and Hazards

GHS Hazard Statements

• H315 (11.8%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (11.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (11.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (11.8%)
• Eye Irrit. 2A (11.8%)
• STOT SE 3 (11.8%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.