Atomfair Trimethylsilyl methanesulfonate TMS-OMs C4H12O3SSi CAS 10090-05-8

Description

Trimethylsilyl methanesulfonate (CAS No. 10090-05-8) is a highly versatile organosilicon reagent with the molecular formula C₄H₁₂O₃SSi. This compound is widely recognized for its role as a silylating agent in organic synthesis, particularly in the protection of hydroxyl groups and activation of carboxylic acids. It is a clear, colorless to pale yellow liquid with a characteristic odor, offering excellent reactivity under mild conditions. Ideal for laboratory and industrial applications, Trimethylsilyl methanesulfonate is rigorously tested for purity and consistency, ensuring reliable performance in sensitive chemical processes. Packaged under inert conditions to maintain stability, this product is a must-have for researchers and chemists working in pharmaceuticals, agrochemicals, and material science.

Properties

• CAS Number: 10090-05-8
• Complexity: 171
• IUPAC Name: trimethylsilyl methanesulfonate
• InChI: InChI=1S/C4H12O3SSi/c1-8(5,6)7-9(2,3)4/h1-4H3
• InChI Key: BCHASIUOFGDRIO-UHFFFAOYSA-N
• Exact Mass: 168.02764195
• Molecular Formula: C4H12O3SSi
• Molecular Weight: 168.29
• SMILES: C[Si](C)(C)OS(=O)(=O)C
• Topological: 51.8
• Monoisotopic Mass: 168.02764195
• Synonyms: Trimethylsilyl methanesulfonate, Trimethylsilyl methanesulphonate, DTXSID70905831, DTXCID901334932, 233-220-2, 10090-05-8, (Trimethylsilyl)methanesulfonate, Silanol, 1,1,1-trimethyl-, 1-methanesulfonate, Methanesulfonic acid, TMS derivative, Silanol, trimethyl-, methanesulfonate, C4H12O3SSi, EINECS 233-220-2, MFCD00042815, CH3SO3Si(CH3)3, Trimethylsilyl methansulfonate, SCHEMBL537775, AKOS015852399, AS-79931, NS00047258, E85347

Trimethylsilyl methanesulfonate is primarily used as a silylating agent to protect hydroxyl groups in synthetic organic chemistry. It facilitates the formation of silyl ethers, which are intermediates in multi-step synthesis. Additionally, it serves as an activating reagent for carboxylic acids, enabling esterification and amidation reactions. Its mild reaction conditions make it suitable for sensitive substrates. This compound is also employed in the preparation of specialty chemicals and advanced materials.

Safety and Hazards

GHS Hazard Statements

• H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.