Atomfair Trifluoromethylsulfonamide CH2F3NO2S

Description Trifluoromethylsulfonamide (CAS No. 421-85-2) is a high-purity fluorinated sulfonamide compound with the molecular formula CH2F3NO2S and IUPAC name trifluoromethanesulfonamide . This specialized chemical is widely utilized in organic synthesis, pharmaceutical research, and materials science due to its strong electron-withdrawing properties and stability under reactive conditions. It serves as a versatile building block for the introduction of the trifluoromethylsulfonyl (CF3SO2-) group, enabling the synthesis of advanced intermediates, catalysts, and bioactive molecules. Available in rigorously controlled batches, our product meets stringent quality standards for researchers requiring precise reactivity and consistency. Suitable for use in nucleophilic substitution reactions, cross-coupling protocols, and as…

Description

Trifluoromethylsulfonamide (CAS No. 421-85-2) is a high-purity fluorinated sulfonamide compound with the molecular formula CH₂F₃NO₂S and IUPAC name trifluoromethanesulfonamide. This specialized chemical is widely utilized in organic synthesis, pharmaceutical research, and materials science due to its strong electron-withdrawing properties and stability under reactive conditions. It serves as a versatile building block for the introduction of the trifluoromethylsulfonyl (CF₃SO₂-) group, enabling the synthesis of advanced intermediates, catalysts, and bioactive molecules. Available in rigorously controlled batches, our product meets stringent quality standards for researchers requiring precise reactivity and consistency. Suitable for use in nucleophilic substitution reactions, cross-coupling protocols, and as a precursor for sulfonamide-based ligands.

CAS No: 421-85-2
Molecular Formula: CH2F3NO2S
Molecular Weight: 149.09
Exact Mass: 148.97583397
Monoisotopic Mass: 148.97583397
IUPAC Name: trifluoromethanesulfonamide
SMILES: C(F)(F)(F)S(=O)(=O)N
Synonyms: Trifluoromethanesulfonamide, 421-85-2, Trifluoromethylsulfonamide, 1,1,1-trifluoromethanesulfonamide, Trifluoromethyl sulfonamide

Application

Trifluoromethylsulfonamide is employed as a key reagent in the synthesis of sulfonamide derivatives for pharmaceutical applications, particularly in the development of enzyme inhibitors and receptor modulators. Its electron-deficient nature makes it valuable in catalysis and as a stabilizing group in organometallic complexes. Researchers also utilize it to construct fluorinated polymers and specialty materials with enhanced thermal and chemical resistance.

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