Description

Trifluoroethanol (CAS No. 75-89-8) is a high-purity fluorinated alcohol with the molecular formula C₂H₃F₃O, widely utilized in pharmaceutical, chemical, and materials research. This versatile solvent exhibits exceptional properties, including strong hydrogen bonding capacity, low nucleophilicity, and high thermal stability, making it ideal for peptide synthesis, polymer studies, and as a co-solvent in biophysical applications. Our product is rigorously tested to ensure ≥99% purity (GC), with stringent controls for water content and acidic impurities. Available in amber glass bottles or bulk packaging to minimize light and moisture exposure, it is an essential reagent for laboratories requiring precision and reliability.

Properties

• CAS Number: 75-89-8
• Complexity: 38.5
• IUPAC Name: 2,2,2-trifluoroethanol
• InChI: InChI=1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2
• InChI Key: RHQDFWAXVIIEBN-UHFFFAOYSA-N
• Exact Mass: 100.01359920
• Molecular Formula: C2H3F3O
• Molecular Weight: 100.04
• SMILES: C(C(F)(F)F)O
• Topological: 20.2
• Monoisotopic Mass: 100.01359920
• Physical Description: Liquid
• Vapor Pressure: 71.3 [mmHg]
• Synonyms: 2,2,2-TRIFLUOROETHANOL, 75-89-8, Trifluoroethanol, Ethanol, 2,2,2-trifluoro-, Trifluoroethyl alcohol, CF3CH2OH, Perfluoro-1,1-dihydroethanol, 2,2,2-trifluoro-ethanol, EINECS 200-913-6, UNII-8T8I76KYF1, BRN 1733203, DTXSID0021751, CHEBI:42330, AI3-25486, NSC-451, 2,2,2trifluoroethanol, TRIFLUOROETHANOL [MI], DTXCID401751, EC 200-913-6, ETHANOL,2,2,2-TRIFLUORO, 4-01-00-01370 (Beilstein Handbook Reference), Alcohol, Trifluoroethyl, Ethanol, 2,2,2trifluoro, 2,2,2Trifluoroethyl alcohol, beta,beta,betaTrifluoroethyl alcohol, UN1986, 200-913-6, inchi=1/c2h3f3o/c3-2(4,5)1-6/h6h,1h, rhqdfwaxviiebn-uhfffaoysa-n, 2,2,2-Trifluoroethan-1-Ol, 2,2,2-Trifluoroethyl alcohol, Fluorinol 85, TFE, NSC 451, beta,beta,beta-Trifluoroethyl alcohol, MFCD00004672, trifluoro ethanol, 8T8I76KYF1, .beta.,.beta.,.beta.-Trifluoroethyl alcohol, MFCD00082609, ETF, 2,2,2-TRIFLUORETHANOL, trifluorethanol, trifluroethanol, C2H3F3O, BETA,BETA,BETA-TRIFLUOROETHANOL, 2,2-Trifluoroethanol, 2,2,-trifluoroethanol, 2,2,2-trifluoroetanol, 2,2,2-trifluoroethoxy, 2,2,2-trifluroethanol, 2,2,2 trifluoroethanol, 2.2,2-trifluoroethanol, 2.2.2-trifluoroethanol, 2,2,2-trifluoroethanole, WLN: Q1XFFF, 2,2,2-trifloro ethanol, 2,2,2 trifluoro-ethanol, 2,2,2,-trifluoroethanol, 2,2,2-tri-fluoroethanol, 2,2,2-trifluoro ethanol, 2,2-Trifluoroethyl alcohol, SCHEMBL4869, SCHEMBL9055, 2,2,2-trifluoro -ethanol, 2,2,2-trifluoroethylalcohol, SCHEMBL27710, 1,1,1-Trifluoro-2-ethanol, CHEMBL116675, SCHEMBL5179073, SCHEMBL8952016, 2,2,2-Trifluoroethanol(TFEA), beta, beta, beta-trifluoroethanol, SEHAXLDZJMQOCZ-UHFFFAOYSA-N, BCP31089, Tox21_200905, 2,2,2-Trifluoroethanol, NMR grade, BBL008539, STK260853, .beta.,.beta.-Trifluoroethyl alcohol, AKOS000119834, DB03226, FT00267, CAS-75-89-8, NCGC00248871-01, NCGC00258459-01, BP-21406, SY349511, VS-01941, NS00008975, ST50705577, T0435, EN300-19568, C93508, 2,2,2-Trifluoroethanol, ReagentPlus(R), >=99%, 2,2,2-Trifluoroethanol redistilled from glass grade, Q2474643, F0001-1907, 2,2,2-Trifluoroethanol, analytical standard, for NMR spectroscopy, Trifluoroethanol;Ethanol, 2,2,2-trifluoro-;Trifluoroethyl alcohol, 2,2,2-Trifluoroethanol, BioUltra, for molecular biology, >=99.0% (GC)

Application

Trifluoroethanol is extensively used as a solvent in peptide and protein research due to its ability to stabilize secondary structures. It serves as a co-solvent in NMR spectroscopy to enhance solubility of hydrophobic compounds. In polymer science, it aids in dissolving and characterizing fluoropolymers and polyesters. Additionally, it is employed as an intermediate in pharmaceutical synthesis and as a degreasing agent in electronics manufacturing.

Safety and Hazards

GHS Hazard Statements

• H226: Flammable liquid and vapor [Warning Flammable liquids]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (99.4%)
• Acute Tox. 3 (91.1%)
• Acute Tox. 4 (59.2%)
• Skin Irrit. 2 (55.6%)
• Eye Dam. 1 (91.7%)
• Acute Tox. 3 (51.5%)
• Acute Tox. 4 (39.6%)
• STOT SE 3 (29%)
• Repr. 1B (20.1%)
• Repr. 1B (17.8%)
• STOT RE 2 (62.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.