Description

Thieno(3,2-b)pyridin-7-ol (CAS No. 107818-20-2) is a high-purity heterocyclic compound with the molecular formula C₇H₅NOS. This specialized chemical is widely utilized in pharmaceutical research, organic synthesis, and material science due to its unique thienopyridine scaffold. Our product is rigorously tested for quality, ensuring >94% purity (HPLC) and optimal stability under recommended storage conditions. Ideal for researchers developing novel bioactive molecules, this compound serves as a versatile building block for drug discovery, particularly in kinase inhibitors and CNS-targeting agents. Each batch is supplied with comprehensive analytical data (NMR, MS, HPLC) and handled under strict GMP-compliant protocols to guarantee reproducibility for your critical experiments.

Properties

• CAS Number: 107818-20-2
• Complexity: 190
• IUPAC Name: 4H-thieno[3,2-b]pyridin-7-one
• InChI: InChI=1S/C7H5NOS/c9-6-1-3-8-5-2-4-10-7(5)6/h1-4H,(H,8,9)
• InChI Key: AACVULYSNJAKEQ-UHFFFAOYSA-N
• Exact Mass: 151.00918496
• Molecular Formula: C7H5NOS
• Molecular Weight: 151.19
• SMILES: C1=CNC2=C(C1=O)SC=C2
• Topological: 57.3
• Monoisotopic Mass: 151.00918496
• Synonyms: Thieno[3,2-b]pyridin-7-ol, 107818-20-2, Thieno(3,2-B)pyridin-7-OL, DTXSID20408069, DTXCID90358921, 626-962-7, thieno[3,2-b]pyridin-7(4H)-one, 69627-02-7, 4H-thieno[3,2-b]pyridin-7-one, THIENO(3 2-B)PYRIDIN-7-OL, 7-HYDROXYTHIENO[3,2-B]PYRIDINE, MFCD01863636, thiopheno[3,2-b]pyridin-7-ol, MFCD12964174, BIDD:GT0268, SCHEMBL105581, thieno[3,2,b]pyridin-7-ol, SCHEMBL1497985, SCHEMBL27915712, Thieno-(3,2-B)-pyridin-7-ol, 4H-thieno[3,2-b]pyridine-7-one, BCP27004, CX1280, SBB071463, Thieno[3,2-b]pyridin-7-ol, 94%, AKOS009156544, AKOS015918999, AC-4399, CS-W002859, FS-2637, PB32284, SB10353, ST094914, SY004858, DB-001091, DB-015056, CS-0166785, H1603, EN300-84887, Q27466710, Z1948933786, Thieno[3,2-b]pyridin-7(4H)-one;7-Hydroxythieno[3,2-b]pyridine

Thieno(3,2-b)pyridin-7-ol serves as a key intermediate in the synthesis of pharmacologically active compounds, particularly kinase inhibitors and neuroactive agents. Researchers employ this heterocycle in medicinal chemistry programs targeting protein-protein interactions and allosteric modulation sites. Its fused ring system enables π-stacking interactions in drug design, while the hydroxyl group allows for further functionalization via etherification or cross-coupling reactions. The compound has shown promise in early-stage development of antiviral and anticancer therapeutics.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.8%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.