Description

Description

Tetrahydropyran-4-boronic acid (CAS No. 1072952-46-5) is a high-purity boronic acid derivative with the molecular formula C₅H₁₁BO₃. This compound, also known by its IUPAC name oxan-4-ylboronic acid, is a versatile building block in organic synthesis and pharmaceutical research. Its unique tetrahydropyran ring structure makes it a valuable intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in complex molecular architectures. This product is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring consistent performance in sensitive applications. It is stable under inert conditions but should be stored in a cool, dry place to prevent degradation. Ideal for researchers in medicinal chemistry, materials science, and catalysis, this boronic acid derivative is packaged in amber glass vials under nitrogen atmosphere to guarantee longevity and quality.

Application

Tetrahydropyran-4-boronic acid is widely used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals via Suzuki-Miyaura cross-coupling reactions. Its tetrahydropyran moiety is particularly valuable in drug discovery for modifying pharmacokinetic properties of lead compounds. Researchers also employ it in the development of boron-containing materials for optoelectronic applications. The compound’s stability and reactivity make it suitable for automated parallel synthesis platforms.

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