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Atomfair tert-Butyl 7-azaspiro[3.5]nonan-2-ylcarbamate C13H24N2O2

Description tert-Butyl 7-azaspiro[3.5]nonan-2-ylcarbamate (CAS No. 147611-03-8) is a high-purity, nitrogen-containing heterocyclic compound with the molecular formula C13H24N2O2. This specialized chemical features a 7-azaspiro[3.5]nonane core structure, offering unique steric and electronic properties valuable in medicinal chemistry and drug discovery. The tert-butoxycarbonyl (Boc) protecting group enhances stability while allowing selective deprotection under mild acidic conditions. Supplied as a white to off-white crystalline powder with ??95% purity (HPLC), this building block is ideal for peptide synthesis, scaffold diversification, and pharmaceutical intermediate applications. Store under inert atmosphere at 2-8??C for optimal stability. Available in research quantities (100mg to 10g) with optional analytical certificates.

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Description

Description

tert-Butyl 7-azaspiro[3.5]nonan-2-ylcarbamate (CAS No. 147611-03-8) is a high-purity, nitrogen-containing heterocyclic compound with the molecular formula C13H24N2O2. This specialized chemical features a 7-azaspiro[3.5]nonane core structure, offering unique steric and electronic properties valuable in medicinal chemistry and drug discovery. The tert-butoxycarbonyl (Boc) protecting group enhances stability while allowing selective deprotection under mild acidic conditions. Supplied as a white to off-white crystalline powder with ??95% purity (HPLC), this building block is ideal for peptide synthesis, scaffold diversification, and pharmaceutical intermediate applications. Store under inert atmosphere at 2-8??C for optimal stability. Available in research quantities (100mg to 10g) with optional analytical certificates.

  • CAS No: 147611-03-8
  • Molecular Formula: C13H24N2O2
  • Molecular Weight: 240.34
  • Exact Mass: 240.183778013
  • Monoisotopic Mass: 240.183778013
  • IUPAC Name: tert-butyl N-(7-azaspiro[3.5]nonan-2-yl)carbamate
  • SMILES: CC(C)(C)OC(=O)NC1CC2(C1)CCNCC2
  • Synonyms: 147611-03-8, tert-Butyl 7-azaspiro[3.5]nonan-2-ylcarbamate, TERT-BUTYL N-(7-AZASPIRO[3.5]NONAN-2-YL)CARBAMATE, tert-butyl N-{7-azaspiro[3.5]nonan-2-yl}carbamate, MFCD12198553

Application

This Boc-protected azaspiro compound serves as a versatile intermediate in organic synthesis, particularly for constructing constrained peptidomimetics and bioactive molecules. The spirocyclic framework induces conformational restriction, making it valuable for structure-activity relationship (SAR) studies in drug discovery. Researchers utilize it in developing CNS-targeting therapeutics due to its ability to modulate blood-brain barrier penetration. The Boc group enables straightforward incorporation into solid-phase peptide synthesis protocols.

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