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Atomfair Tert-butyl 4-(6-(methoxycarbonyl)pyridin-3-yl)piperazine-1-carboxylate C16H23N3O4

Description Tert-butyl 4-(6-(methoxycarbonyl)pyridin-3-yl)piperazine-1-carboxylate (CAS: 1354355-85-3) is a high-purity chemical compound with the molecular formula C16H23N3O4. This specialized intermediate features a piperazine core functionalized with a tert-butoxycarbonyl (Boc) protecting group and a methoxycarbonyl-substituted pyridine moiety, making it a valuable building block in medicinal chemistry and pharmaceutical research. The compound is characterized by its high stability under standard conditions and is supplied as a white to off-white crystalline solid with ??95% purity (HPLC). Suitable for use in peptide coupling reactions, Suzuki-Miyaura cross-couplings, and other palladium-catalyzed transformations, this reagent is meticulously packaged under inert gas to ensure long-term stability. Each batch undergoes rigorous…

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Description

Description

Tert-butyl 4-(6-(methoxycarbonyl)pyridin-3-yl)piperazine-1-carboxylate (CAS: 1354355-85-3) is a high-purity chemical compound with the molecular formula C16H23N3O4. This specialized intermediate features a piperazine core functionalized with a tert-butoxycarbonyl (Boc) protecting group and a methoxycarbonyl-substituted pyridine moiety, making it a valuable building block in medicinal chemistry and pharmaceutical research. The compound is characterized by its high stability under standard conditions and is supplied as a white to off-white crystalline solid with ??95% purity (HPLC). Suitable for use in peptide coupling reactions, Suzuki-Miyaura cross-couplings, and other palladium-catalyzed transformations, this reagent is meticulously packaged under inert gas to ensure long-term stability. Each batch undergoes rigorous QC analysis (NMR, LC-MS) to guarantee consistency for research applications.

  • CAS No: 1354355-85-3
  • Molecular Formula: C16H23N3O4
  • Molecular Weight: 321.37
  • Exact Mass: 321.16885622
  • Monoisotopic Mass: 321.16885622
  • IUPAC Name: tert-butyl 4-(6-methoxycarbonylpyridin-3-yl)piperazine-1-carboxylate
  • SMILES: CC(C)(C)OC(=O)N1CCN(CC1)C2=CN=C(C=C2)C(=O)OC
  • Synonyms: 1354355-85-3, tert-butyl 4-(6-(methoxycarbonyl)pyridin-3-yl)piperazine-1-carboxylate, tert-butyl 4-[6-(methoxycarbonyl)pyridin-3-yl]piperazine-1-carboxylate, SCHEMBL14802410, YHMGGJCKQSNUID-UHFFFAOYSA-N

Application

This compound serves as a key intermediate in the synthesis of biologically active molecules, particularly in the development of kinase inhibitors and GPCR-targeting pharmaceuticals. Its Boc-protected piperazine group allows for selective deprotection and further functionalization in multi-step syntheses. Researchers utilize this building block in fragment-based drug discovery (FBDD) and combinatorial chemistry libraries. The pyridine ester moiety also enables downstream derivatization via hydrolysis or amide coupling.

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