Atomfair

Awaiting product image

Atomfair tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate C16H30BNO4

Description tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate (CAS: 1048970-17-7) is a high-purity boronic ester derivative extensively utilized in organic synthesis and pharmaceutical research. This compound, with the molecular formula C16H30BNO4, features a piperidine core protected by a tert-butoxycarbonyl (Boc) group and a reactive pinacol boronate ester moiety, making it an invaluable intermediate for Suzuki-Miyaura cross-coupling reactions. Its stability under inert conditions ensures reliable performance in complex synthetic pathways. Ideal for researchers developing novel bioactive molecules or materials, this reagent is rigorously tested for consistency and purity, meeting the stringent demands of modern laboratories. Available in various quantities, it is supplied with comprehensive analytical data…

Category:
Brands:

Description

Description

tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate (CAS: 1048970-17-7) is a high-purity boronic ester derivative extensively utilized in organic synthesis and pharmaceutical research. This compound, with the molecular formula C16H30BNO4, features a piperidine core protected by a tert-butoxycarbonyl (Boc) group and a reactive pinacol boronate ester moiety, making it an invaluable intermediate for Suzuki-Miyaura cross-coupling reactions. Its stability under inert conditions ensures reliable performance in complex synthetic pathways. Ideal for researchers developing novel bioactive molecules or materials, this reagent is rigorously tested for consistency and purity, meeting the stringent demands of modern laboratories. Available in various quantities, it is supplied with comprehensive analytical data (NMR, HPLC, MS) to guarantee quality and reproducibility.

  • CAS No: 1048970-17-7
  • Molecular Formula: C16H30BNO4
  • Molecular Weight: 311.2
  • Exact Mass: 311.2267886
  • Monoisotopic Mass: 311.2267886
  • IUPAC Name: tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2CCN(CC2)C(=O)OC(C)(C)C
  • Synonyms: 1048970-17-7, tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate, DTXSID50656455, DTXCID50607205, 686-917-2

Application

This compound serves as a versatile building block in medicinal chemistry, particularly for the synthesis of boron-containing pharmaceuticals via palladium-catalyzed cross-coupling reactions. Its Boc-protected piperidine scaffold is instrumental in constructing kinase inhibitors and CNS-targeting agents. The pinacol boronate group enhances solubility and reactivity in aqueous conditions, facilitating bioconjugation and labeling applications. Researchers also employ it in the development of PET radiotracers due to its potential for 18F-incorporation.

If you are interested or have any questions, please contact us at support@atomfair.com