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Atomfair tert-Butyl 3,4-dihydroquinoline-1(2H)-carboxylate 1-BOC-THQ, Boc-Tetrahydroquinoline C14H19NO2

Description tert-Butyl 3,4-dihydroquinoline-1(2H)-carboxylate (CAS No. 123387-53-1) is a high-purity synthetic organic compound with the molecular formula C14H19NO2. This Boc-protected tetrahydroquinoline derivative is widely utilized in pharmaceutical research, medicinal chemistry, and as a versatile intermediate in organic synthesis. The compound features a tert -butyloxycarbonyl (Boc) protecting group, which enhances stability and facilitates selective deprotection during multi-step synthetic processes. With a molecular weight of 233.31 g/mol, it is supplied as a crystalline solid or powder, typically with ??95% purity (HPLC). Ideal for N-heterocycle functionalization, this reagent is rigorously tested for consistency and is available in research (1 kg) quantities. Store under inert…

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Description

Description

tert-Butyl 3,4-dihydroquinoline-1(2H)-carboxylate (CAS No. 123387-53-1) is a high-purity synthetic organic compound with the molecular formula C14H19NO2. This Boc-protected tetrahydroquinoline derivative is widely utilized in pharmaceutical research, medicinal chemistry, and as a versatile intermediate in organic synthesis. The compound features a tert-butyloxycarbonyl (Boc) protecting group, which enhances stability and facilitates selective deprotection during multi-step synthetic processes. With a molecular weight of 233.31 g/mol, it is supplied as a crystalline solid or powder, typically with ??95% purity (HPLC). Ideal for N-heterocycle functionalization, this reagent is rigorously tested for consistency and is available in research (<1 g), development (10-100 g), and bulk (>1 kg) quantities. Store under inert atmosphere at 2-8??C to maintain optimal stability.

  • CAS No: 123387-53-1
  • Molecular Formula: C14H19NO2
  • Molecular Weight: 233.31
  • Exact Mass: 233.141578849
  • Monoisotopic Mass: 233.141578849
  • IUPAC Name: tert-butyl 3,4-dihydro-2H-quinoline-1-carboxylate
  • SMILES: CC(C)(C)OC(=O)N1CCCC2=CC=CC=C21
  • Synonyms: 123387-53-1, tert-Butyl 3,4-dihydroquinoline-1(2H)-carboxylate, 1-BOC-1,2,3,4-Tetrahydroquinoline, Tert-butyl 3,4-dihydro-2H-quinoline-1-carboxylate, 1(2H)-Quinolinecarboxylic acid, 3,4-dihydro-, 1,1-dimethylethyl ester

Application

This Boc-protected tetrahydroquinoline serves as a key building block in the synthesis of bioactive alkaloids and pharmaceutical compounds. Researchers employ it in palladium-catalyzed cross-coupling reactions for quinoline ring functionalization. The compound is particularly valuable in developing CNS-active molecules due to the privileged tetrahydroquinoline scaffold. Its Boc group allows for orthogonal protection strategies in peptide-mimetic and combinatorial chemistry applications.

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