Description

Description

tert-Butyl 2,5-diazaspiro[3.4]octane-5-carboxylate (CAS No. 1086398-04-0) is a high-purity, nitrogen-containing spirocyclic compound with the molecular formula C₁₁H₂₀N₂O₂. This Boc-protected diazaspiro derivative is a valuable intermediate in organic synthesis and pharmaceutical research, particularly for the development of novel bioactive molecules and drug candidates. Its unique spiro[3.4]octane scaffold offers steric and conformational constraints that are highly desirable in medicinal chemistry for modulating target interactions. The compound is supplied as a white to off-white solid with ??95% purity (HPLC) and is rigorously characterized by ¹H NMR, ¹³C NMR, and mass spectrometry. Suitable for use in peptide mimetics, heterocyclic chemistry, and as a building block for kinase inhibitors or GPCR-targeted compounds. Packaged under inert atmosphere to ensure stability and shipped with comprehensive analytical data.

Application

This Boc-protected diazaspiro compound serves as a versatile scaffold in medicinal chemistry, particularly for designing constrained peptidomimetics and small molecule inhibitors. Researchers utilize it to introduce three-dimensional complexity into drug candidates, improving target selectivity and metabolic stability. The spirocyclic structure is valuable for probing protein-ligand interactions in kinase and receptor-based drug discovery programs. It’s also employed in the synthesis of novel heterocycles for chemical biology studies.

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