Description

Suplatast Tosilate (CAS No. 94055-76-2) is a high-purity sulfonium salt derivative with the molecular formula C₂₃H₃₃NO₇S₂. This compound, also known by its IUPAC name [3-[4-(3-ethoxy-2-hydroxypropoxy)anilino]-3-oxopropyl]-dimethylsulfanium;4-methylbenzenesulfonate, is a selective Th2 cytokine inhibitor with potential applications in immunology and respiratory research. Our Suplatast Tosilate is rigorously tested for quality, ensuring ≥98% purity by HPLC, and is provided as a white to off-white crystalline powder. It is soluble in DMSO and ethanol but exhibits limited solubility in aqueous solutions. Each batch is accompanied by comprehensive analytical data including NMR, MS, and chromatographic profiles to guarantee reproducibility for your research needs. Available in convenient packaging options from milligrams to bulk quantities, this product is ideal for in vitro and in vivo studies investigating allergic responses and immune modulation.

Properties

• CAS Number: 94055-76-2
• Complexity: 500
• IUPAC Name: [3-[4-(3-ethoxy-2-hydroxy-propoxy)anilino]-3-oxo-propyl]-dimethyl-sulfonium;4-methylbenzenesulfonate
• InChI: InChI=1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)
• InChI Key: RYVJQEZJUFRANT-UHFFFAOYSA-N
• Exact Mass: 499.16984474
• Molecular Formula: C23H33NO7S2
• Molecular Weight: 499.6
• SMILES: CCOCC(COC1=CC=C(C=C1)NC(=O)CC[S+](C)C)O.CC1=CC=C(C=C1)S(=O)(=O)[O-]
• Topological: 134
• Monoisotopic Mass: 499.16984474
• Synonyms: Suplatast Tosilate, Suplatast tosylate, 94055-76-2, IPD-1151T, Ipd 1151T, Suplatast tosilate [INN], Tosilate de suplatast, Tosilato de suplatast, Suplatastum tosilas, CCRIS 6596, Suplatastum tosilas [INN-Latin], Tosilate de suplatast [INN-French], Tosilato de suplatast [INN-Spanish], (3-((4-(3-ethoxy-2-hydroxypropoxy)phenyl)amino)-3-oxopropyl)dimethylsulfonium 4-methylbenzenesulfonate, DTXSID9045003, C9J89787U1, SUPLATAST TOSYLATE [MI], DTXCID7025003, SUPLATAST TOSILATE [JAN], SUPLATAST TOSILATE [MART.], SUPLATAST TOSILATE [WHO-DD], (+-)-(2-(4-(3-Ethoxy-2-hydroxypropoxy)phenyl)carbamoyl)ethyldimethylsulfonium p-tosylate, Sulfonium, (3-((4-(3-ethoxy-2-hydroxypropoxy)phenyl)amino)-3-oxopropyl)dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1), Suplatastum tosilas (INN-Latin), SUPLATAST TOSILATE (MART.), Tosilate de suplatast (INN-French), Tosilato de suplatast (INN-Spanish), [3-[[4-(3-Ethoxy-2-hydroxypropoxy)phenyl]amino]-3-oxopropyl]dimethylsulfonium 4-methylbenzenesulfonate, suplatasti tosilas, (2-(4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl)ethyl)dimethylsulfonium p-toluenesulfonate, 692-147-8, Suplatast (Tosilate), 94055-76-2 (tosylate), MFCD00867604, Suplatasttosilate, CAS-94055-76-2, NCGC00181000-01, UNII-C9J89787U1, YM-672, IPD (TN), SCHEMBL29042, MLS006010745, Suplatast tosilate (JAN/INN), CHEMBL115435, HMS3413P08, HMS3655L09, HMS3677P08, HMS5080F15, BCP10310, Tox21_112652, s2015, Suplatast tosylate, >=98% (HPLC), AKOS015900359, Tox21_112652_1, CCG-269685, CS-0574, KS-1288, NCGC00181000-02, (+-)-(2-((p-(3-Ethoxy-2-hydroxypropoxy)phenyl)carbamoyl)ethyl)dimethylsulfonium p-toluenesulfonate, [3-[4-(3-ethoxy-2-hydroxypropoxy)anilino]-3-oxopropyl]-dimethylsulfanium;4-methylbenzenesulfonate, HY-17002, SMR004701701, NS00121209, S0875, SW219352-1, C77240, D01423, SBI-0654199.0001, Q7644399, 2-[4-(3-Ethoxy-2-hydroxypropoxy)phenylcarbamoyl]ethyldimethylsulfonium p-Toluenesulfonate, (+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate

Application

Suplatast Tosilate is primarily investigated as a Th2 cytokine inhibitor for research in allergic diseases such as asthma and atopic dermatitis. It demonstrates selective suppression of interleukin-4 and interleukin-5 production, making it valuable for studying IgE-mediated immune responses. Researchers utilize this compound to explore mechanisms of eosinophil infiltration and airway hyperresponsiveness in respiratory models.

Safety and Hazards

GHS Hazard Statements

• H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Precautionary Statements

• P203, P280, P318, P405, and P501

Hazard Classes and Categories

• Repr. 2 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.