Description

(R)-Styrene Oxide is a high-purity chiral epoxide widely used in organic synthesis, pharmaceutical research, and asymmetric catalysis. This compound, with the molecular formula C₈H₈O and CAS number 20780-53-4, is characterized by its enantiomeric purity, making it an essential building block for the production of optically active compounds. Its (R)-configuration ensures precise stereochemical outcomes in reactions, critical for drug development and fine chemical manufacturing. Available in various grades, including ≥98% purity with optical purity up to 97% ee (GLC), this product is rigorously tested to meet the stringent requirements of researchers and industrial applications. Packaged under inert conditions to maintain stability, it is ideal for use in nucleophilic ring-opening reactions, polymerization studies, and chiral auxiliary synthesis.

Properties

• CAS Number: 20780-53-4
• Complexity: 94.7
• IUPAC Name: (2R)-2-phenyloxirane
• InChI: InChI=1S/C8H8O/c1-2-4-7(5-3-1)8-6-9-8/h1-5,8H,6H2/t8-/m0/s1
• InChI Key: AWMVMTVKBNGEAK-QMMMGPOBSA-N
• Exact Mass: 120.057514874
• Molecular Formula: C8H8O
• Molecular Weight: 120.15
• SMILES: C1[C@H](O1)C2=CC=CC=C2
• Topological: 12.5
• Monoisotopic Mass: 120.057514874
• Synonyms: (R)-Styrene oxide, R-Phenyloxirane, (2R)-2-phenyloxirane, (R)-(+)-Styrene oxide, R-STYRENE OXIDE, (R)-(Epoxyethyl)benzene, Oxirane, 2-phenyl-, (2R)-, Oxirane, phenyl-, (2R)-, Styrene oxide, (R)-, Benzene, (epoxyethyl)-, (R)-, 0HB27D5MRW, CCRIS 4093, CHEBI:45389, (+)-PHENYLOXIRANE, (+)-(R)-STYRENE OXIDE, (R)-STYRENE 7,8-OXIDE, DTXSID401349483, Benzene, (epoxyethyl)-, (R)-(+)-, DTXCID701778495, 606-637-6, 20780-53-4, (R)-2-phenyloxirane, (R)-Phenyloxirane, (R)-Phenylethylene oxide, (R)-1,2-Epoxyethylbenzene, (R)-2-PHENYL-OXIRANE, MFCD00066210, (S)-(-)-Styrene oxide, 2-Phenyloxirane #, (-)-R-Epoxystyrene, (r)-(+)-styreneoxide, (S)-(-)-Phenyloxirane, (r)-(+) styrene oxide, (R)-BENZEN, UNII-0HB27D5MRW, MLS001066357, BIDD:ER0688, SCHEMBL1943997, (R)-(-)-(Epoxyethyl)benzene, CHEMBL1235743, NIOSH/CZ9625020, HMS2231G06, (R)-(+)-Styrene oxide, 98%, AKOS015900618, Benzene, (epoxyethyl)-, (R)-(-)-, CS-W013577, DB04499, AS-12169, RSO, SMR000471848, CZ96250200, NS00120264, S0516, EN300-250892, F20441, Q27095270, Z1255356265, (R)-(+)-Styrene oxide, 97%, optical purity ee: 97% (GLC), (R)-(+)-Styrene oxide, ChiPros(R), produced by BASF, >=98%

(R)-Styrene Oxide is extensively utilized as a chiral intermediate in pharmaceutical synthesis, particularly for producing enantiomerically pure drugs. It serves as a key precursor in asymmetric catalysis and polymerization reactions, enabling the creation of advanced materials. Researchers also employ it in mechanistic studies of epoxide ring-opening reactions due to its well-defined stereochemistry.

Safety and Hazards

GHS Hazard Statements

• H312 (98.2%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H350 (100%): May cause cancer [Danger Carcinogenicity]

Precautionary Statements

• P203, P264+P265, P280, P302+P352, P305+P351+P338, P317, P318, P321, P337+P317, P362+P364, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (98.2%)
• Eye Irrit. 2 (100%)
• Carc. 1B (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.