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Atomfair Sonlicromanol KH-176, KH176 C19H28N2O3 CAS 1541170-75-5

Sonlicromanol (CAS No. 1541170-75-5) is a high-purity small molecule with the molecular formula C19H28N2O3, and IUPAC name (2S)-6-hydroxy-2,5,7,8-tetramethyl-N-[(3R)-piperidin-3-yl]-3,4-dihydrochromene-2-carboxamide . This compound, also known by its developmental code KH-176 , is a redox-modulating agent under investigation for its therapeutic potential in mitochondrial disorders. It exhibits high stability and solubility profiles, making it suitable for in vitro and in vivo research applications. Our product is rigorously tested via HPLC, NMR, and mass spectrometry to ensure ≥98% purity, meeting the stringent requirements of pharmaceutical and biochemical research. Available in milligram to gram quantities with custom bulk options.

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Description

Sonlicromanol (CAS No. 1541170-75-5) is a high-purity small molecule with the molecular formula C19H28N2O3, and IUPAC name (2S)-6-hydroxy-2,5,7,8-tetramethyl-N-[(3R)-piperidin-3-yl]-3,4-dihydrochromene-2-carboxamide. This compound, also known by its developmental code KH-176, is a redox-modulating agent under investigation for its therapeutic potential in mitochondrial disorders. It exhibits high stability and solubility profiles, making it suitable for in vitro and in vivo research applications. Our product is rigorously tested via HPLC, NMR, and mass spectrometry to ensure ≥98% purity, meeting the stringent requirements of pharmaceutical and biochemical research. Available in milligram to gram quantities with custom bulk options.

Properties

  • CAS Number: 1541170-75-5
  • Complexity: 472
  • IUPAC Name: (2S)-6-hydroxy-2,5,7,8-tetramethyl-N-[(3R)-3-piperidyl]chromane-2-carboxamide
  • InChI: InChI=1S/C19H28N2O3/c1-11-12(2)17-15(13(3)16(11)22)7-8-19(4,24-17)18(23)21-14-6-5-9-20-10-14/h14,20,22H,5-10H2,1-4H3,(H,21,23)/t14-,19+/m1/s1
  • InChI Key: LZYWLEPSQNXESC-KUHUBIRLSA-N
  • Exact Mass: 332.20999276
  • Molecular Formula: C19H28N2O3
  • Molecular Weight: 332.4
  • SMILES: CC1=C(C2=C(CC[C@@](O2)(C)C(=O)N[C@@H]3CCCNC3)C(=C1O)C)C
  • Topological: 70.6
  • Monoisotopic Mass: 332.20999276
  • Synonyms: Sonlicromanol, KH-176, JCU3O35RDS, UNII-JCU3O35RDS, KH176, SONLICROMANOL [INN], sonlicromanolum, (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-Carboxamide, 1541170-75-5, (2S)-3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-N-(3R)-3-piperidinyl-2H-1-benzopyran-2-carboxamide, (2S)-6-hydroxy-2,5,7,8-tetramethyl-N-[(3R)-piperidin-3-yl]-3,4-dihydrochromene-2-carboxamide, 2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-N-(3R)-3-piperidinyl-, (2S)-, KH-176 (Sonlicromanol), CHEMBL4802153, SCHEMBL19235721, EX-A9097, AKOS040752260, HY-121577, CS-0082766, Q27896123

Application

Sonlicromanol (KH-176) is a promising redox modulator studied for its potential in treating mitochondrial diseases, such as Leigh syndrome and MELAS (Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes). It targets oxidative stress by balancing cellular redox states, making it relevant for neurodegenerative and metabolic disorder research. Preclinical studies suggest neuroprotective and energy-restoring effects, supporting further investigation in mitochondrial dysfunction models.

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

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  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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