Description

Saflufenacil (CAS No. 372137-35-4) is a highly effective pyrimidinedione herbicide with the molecular formula C₁₇H₁₇ClF₄N₄O₅S. Known by its IUPAC name 2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]-N-[methyl(propan-2-yl)sulfamoyl]benzamide, this compound is a protoporphyrinogen oxidase (PPO) inhibitor, disrupting chlorophyll biosynthesis in target weeds. Saflufenacil is widely recognized for its rapid burndown activity and residual control, making it a preferred choice for pre-plant and pre-emergence applications in crops like soybeans, corn, and cereals. Its high efficacy against broadleaf weeds, including glyphosate-resistant species, ensures superior crop protection. Available in technical-grade purity (>95%), this product is ideal for research, agrochemical development, and formulation studies. Store in a cool, dry place away from light to maintain stability.

Properties

• CAS Number: 372137-35-4
• Complexity: 921
• IUPAC Name: 2-chloro-4-fluoro-N-[isopropyl(methyl)sulfamoyl]-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]benzamide
• InChI: InChI=1S/C17H17ClF4N4O5S/c1-8(2)25(4)32(30,31)23-15(28)9-5-12(11(19)6-10(9)18)26-14(27)7-13(17(20,21)22)24(3)16(26)29/h5-8H,1-4H3,(H,23,28)
• InChI Key: GNHDVXLWBQYPJE-UHFFFAOYSA-N
• Exact Mass: 500.0544312
• Molecular Formula: C17H17ClF4N4O5S
• Molecular Weight: 500.9
• SMILES: CC(C)N(C)S(=O)(=O)NC(=O)C1=CC(=C(C=C1Cl)F)N2C(=O)C=C(N(C2=O)C)C(F)(F)F
• Topological: 115
• Monoisotopic Mass: 500.0544312
• Synonyms: Saflufenacil, 372137-35-4, Kixor, Kixor Herbicide, Saflufenacil [ISO], saflufenacile, UNII-189U20M808, TREEVIX, SAFLUFENACIL [MI], 2-chloro-5-(3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl)-4-fluoro-N-((methyl(1-methylethyl)amino)sulfonyl)benzamide, DTXSID9058072, CHEBI:142824, 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2h)-pyrimidinyl]-4-fluoro-n-[[methyl(1-methylethyl)amino]sulfonyl]benzamide, N’-{2-chloro-4-fluoro-5-(1,2,3,6-tetrahydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl)benzoyl}-N-isopropyl-N-methylsulfamide, 2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2H)-yl]-N-[methyl(propan-2-yl)sulfamoyl]benzamide, 2-chloro-4-fluoro-N-[isopropyl(methyl)sulfamoyl]-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2H)-yl]benzamide, N’-(2-CHLORO-4-FLUORO-5-(1,2,3,6-TETRAHYDRO-3-METHYL-2,6-DIOXO-4-(TRIFLUOROMETHYL)PYRIMIDIN-1-YL)BENZOYL)-N-ISOPROPYL-N-METHYLSULFAMIDE, N’-{2-chloro-4-fluoro-5-[1,2,3,6-tetrahydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]benzoyl}-N-isopropyl-N-methylsulfamide, 2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2H)-yl)-N-(methyl(propan-2-yl)sulfamoyl)benzamide, 2-chloro-4-fluoro-N-(isopropyl(methyl)sulfamoyl)-5-(3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2H)-yl)benzamide, DTXCID5031840, 619-504-2, n’-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4(trifluoromethyl)-3,6-dihydro-1(2h)-pyrimidinyl)benzoyl)-n-isopropyl-n-methylsulfamide, 189U20M808, 2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]-N-[methyl(propan-2-yl)sulfamoyl]benzamide, Saflufenacil 100 microg/mL in Acetonitrile, SCHEMBL712168, CHEMBL2251845, MSK22654, AKOS027313956, CS-0077912, NS00133850, Saflufenacil, PESTANAL(R), analytical standard, EN300-20356403, Q7398820, 2-Chloro-4-fluoro-N-(isopropyl(methyl)sulfamoyl)-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]benzamide, 2-chloro-4-fluoro-N-[methyl(propan-2-yl)sulfamoyl]-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]benzamide, 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)-pyrimidinyl]-4-fluoro-N-[[methyl-(1-methylethyl)amino]sulfonyl]benzamide, Benzamide, 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]-

Application

Saflufenacil is primarily used as a broad-spectrum herbicide for pre-plant and pre-emergence weed control in row crops, including soybeans and corn. It effectively targets broadleaf weeds such as waterhemp, ragweed, and morning glory by inhibiting PPO, leading to rapid desiccation and plant death. Its soil residual activity provides extended protection against emerging weeds. Researchers utilize Saflufenacil to study herbicide resistance mechanisms and develop sustainable weed management strategies.

Safety and Hazards

GHS Hazard Statements

• H361d (14.9%): Suspected of damaging the unborn child [Warning Reproductive toxicity]
• H400 (44.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
• H410 (44.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P203, P273, P280, P318, P391, P405, and P501

Hazard Classes and Categories

• Repr. 2 (14.9%)
• Aquatic Acute 1 (44.7%)
• Aquatic Chronic 1 (44.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.