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Atomfair (S)-alpha-Methyl-4-Iodophenylalanine alpha-Me-Phe(4-I)-OH C10H12INO2

Description (S)-alpha-Methyl-4-Iodophenylalanine (CAS No. 1215092-16-2) is a high-purity, non-natural amino acid derivative with the molecular formula C10H12INO2. This chiral compound, also known by its IUPAC name (2S)-2-amino-3-(4-iodophenyl)-2-methylpropanoic acid , features a stereocenter at the alpha-carbon and a para-iodinated phenyl ring, making it a valuable building block for peptide modification and pharmaceutical research. With a molecular weight of 305.11 g/mol, this white to off-white crystalline powder is characterized by its high chemical stability and solubility in organic solvents such as DMSO and methanol. Ideal for medicinal chemistry applications, it serves as a key intermediate in the synthesis of bioactive peptides, enzyme…

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Description

Description

(S)-alpha-Methyl-4-Iodophenylalanine (CAS No. 1215092-16-2) is a high-purity, non-natural amino acid derivative with the molecular formula C10H12INO2. This chiral compound, also known by its IUPAC name (2S)-2-amino-3-(4-iodophenyl)-2-methylpropanoic acid, features a stereocenter at the alpha-carbon and a para-iodinated phenyl ring, making it a valuable building block for peptide modification and pharmaceutical research. With a molecular weight of 305.11 g/mol, this white to off-white crystalline powder is characterized by its high chemical stability and solubility in organic solvents such as DMSO and methanol. Ideal for medicinal chemistry applications, it serves as a key intermediate in the synthesis of bioactive peptides, enzyme inhibitors, and radiopharmaceuticals. Each batch is rigorously analyzed by HPLC, NMR, and MS to ensure ??95% purity, meeting the stringent requirements of research and industrial applications.

  • CAS No: 1215092-16-2
  • Molecular Formula: C10H12INO2
  • Molecular Weight: 305.11
  • Exact Mass: 304.99128
  • Monoisotopic Mass: 304.99128
  • IUPAC Name: (2S)-2-amino-3-(4-iodophenyl)-2-methylpropanoic acid
  • SMILES: C[C@](CC1=CC=C(C=C1)I)(C(=O)O)N
  • Synonyms: 1215092-16-2, (S)-alpha-Methyl-4-Iodophenylalanine, alpha-Me-Phe(4-I)-OH, (S)-a-Methyl-4-iodophenylalanine, (S)-2-amino-3-(4-iodophenyl)-2-methylpropanoic acid

Application

(S)-alpha-Methyl-4-Iodophenylalanine is widely used in peptide chemistry as a non-natural amino acid to enhance metabolic stability and modulate peptide-receptor interactions. Its para-iodo substitution makes it valuable in the development of radiolabeled compounds for PET imaging and targeted therapy. Researchers also employ this derivative in structure-activity relationship (SAR) studies to explore steric and electronic effects in drug design.

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