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Atomfair (R)-alpha-Methyl-4-(trifluoromethoxy)phenylalaine alpha-Me-D-Phe(4-OCF3)-OH C11H12F3NO3 CAS 1269835-58-6

(R)-alpha-Methyl-4-(trifluoromethoxy)phenylalaine (CAS No. 1269835-58-6) is a high-purity, non-natural amino acid derivative designed for advanced research applications. With the molecular formula C11H12F3NO3, this compound features a chiral alpha-methyl group and a trifluoromethoxy-substituted phenyl ring, offering unique steric and electronic properties. Its IUPAC name, (2R)-2-amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid , reflects its precise stereochemistry, making it invaluable for peptide modification, medicinal chemistry, and asymmetric synthesis. Packaged under inert conditions to ensure stability, this product is rigorously characterized by HPLC, NMR, and MS to guarantee ≥95% purity. Ideal for pharmaceutical development, enzyme studies, and ligand design, it is available in customizable quantities with batch-specific certificates of…

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Description

(R)-alpha-Methyl-4-(trifluoromethoxy)phenylalaine (CAS No. 1269835-58-6) is a high-purity, non-natural amino acid derivative designed for advanced research applications. With the molecular formula C11H12F3NO3, this compound features a chiral alpha-methyl group and a trifluoromethoxy-substituted phenyl ring, offering unique steric and electronic properties. Its IUPAC name, (2R)-2-amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid, reflects its precise stereochemistry, making it invaluable for peptide modification, medicinal chemistry, and asymmetric synthesis. Packaged under inert conditions to ensure stability, this product is rigorously characterized by HPLC, NMR, and MS to guarantee ≥95% purity. Ideal for pharmaceutical development, enzyme studies, and ligand design, it is available in customizable quantities with batch-specific certificates of analysis.

Properties

  • CAS Number: 1269835-58-6
  • Complexity: 300
  • IUPAC Name: (2R)-2-amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid
  • InChI: InChI=1S/C11H12F3NO3/c1-10(15,9(16)17)6-7-2-4-8(5-3-7)18-11(12,13)14/h2-5H,6,15H2,1H3,(H,16,17)/t10-/m1/s1
  • InChI Key: AYWWOOCNIXIIJO-SNVBAGLBSA-N
  • Exact Mass: 263.07692773
  • Molecular Formula: C11H12F3NO3
  • Molecular Weight: 263.21
  • SMILES: C[C@@](CC1=CC=C(C=C1)OC(F)(F)F)(C(=O)O)N
  • Topological: 72.6
  • Monoisotopic Mass: 263.07692773
  • Synonyms: 1269835-58-6, alpha-Me-D-Phe(4-OCF3)-OH, (R)-alpha-Methyl-4-(trifluoromethoxy)phenylalaine, (2R)-2-amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid, AKOS030213000, D-Tyrosine, |A-methyl-O-(trifluoromethyl)-

Application

This chiral amino acid derivative is widely used in peptide engineering to enhance metabolic stability and bioavailability of therapeutic candidates. Its trifluoromethoxy group serves as a versatile handle for radiolabeling and PET tracer development in imaging studies. Researchers also employ it as a building block for small-molecule inhibitors targeting enzymes or receptors where steric hindrance is critical.

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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