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Atomfair (R)-alpha-Methyl-4-(trifluoromethoxy)phenylalaine alpha-Me-D-Phe(4-OCF3)-OH C11H12F3NO3

Description (R)-alpha-Methyl-4-(trifluoromethoxy)phenylalaine (CAS No. 1269835-58-6) is a high-purity, non-natural amino acid derivative designed for advanced research applications. With the molecular formula C11H12F3NO3, this compound features a chiral alpha-methyl group and a trifluoromethoxy-substituted phenyl ring, offering unique steric and electronic properties. Its IUPAC name, (2R)-2-amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid , reflects its precise stereochemistry, making it invaluable for peptide modification, medicinal chemistry, and asymmetric synthesis. Packaged under inert conditions to ensure stability, this product is rigorously characterized by HPLC, NMR, and MS to guarantee ??95% purity. Ideal for pharmaceutical development, enzyme studies, and ligand design, it is available in customizable quantities with batch-specific certificates…

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Description

Description

(R)-alpha-Methyl-4-(trifluoromethoxy)phenylalaine (CAS No. 1269835-58-6) is a high-purity, non-natural amino acid derivative designed for advanced research applications. With the molecular formula C11H12F3NO3, this compound features a chiral alpha-methyl group and a trifluoromethoxy-substituted phenyl ring, offering unique steric and electronic properties. Its IUPAC name, (2R)-2-amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid, reflects its precise stereochemistry, making it invaluable for peptide modification, medicinal chemistry, and asymmetric synthesis. Packaged under inert conditions to ensure stability, this product is rigorously characterized by HPLC, NMR, and MS to guarantee ??95% purity. Ideal for pharmaceutical development, enzyme studies, and ligand design, it is available in customizable quantities with batch-specific certificates of analysis.

  • CAS No: 1269835-58-6
  • Molecular Formula: C11H12F3NO3
  • Molecular Weight: 263.21
  • Exact Mass: 263.07692773
  • Monoisotopic Mass: 263.07692773
  • IUPAC Name: (2R)-2-amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid
  • SMILES: C[C@@](CC1=CC=C(C=C1)OC(F)(F)F)(C(=O)O)N
  • Synonyms: 1269835-58-6, alpha-Me-D-Phe(4-OCF3)-OH, (R)-alpha-Methyl-4-(trifluoromethoxy)phenylalaine, (2R)-2-amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid, AKOS030213000

Application

This chiral amino acid derivative is widely used in peptide engineering to enhance metabolic stability and bioavailability of therapeutic candidates. Its trifluoromethoxy group serves as a versatile handle for radiolabeling and PET tracer development in imaging studies. Researchers also employ it as a building block for small-molecule inhibitors targeting enzymes or receptors where steric hindrance is critical.

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