Description
(R)-1-(3-Bromopyridin-2-YL)-2,2,2-trifluoroethan-1-amine (CAS: 1213066-11-5) is a high-purity chiral amine derivative featuring a 3-bromopyridine scaffold and a trifluoroethylamine moiety. This compound, with the molecular formula C7H6BrF3N2, is designed for advanced pharmaceutical and agrochemical research, particularly in enantioselective synthesis and medicinal chemistry applications. Its unique stereochemistry and functional groups make it a valuable intermediate for the development of bioactive molecules, including potential drug candidates and catalysts. Packaged under inert conditions to ensure stability, this product is rigorously tested by HPLC, NMR, and mass spectrometry to guarantee ≥95% purity. Ideal for researchers requiring precise chiral building blocks for asymmetric synthesis.
Properties
- CAS Number: 1213066-11-5
- Complexity: 174
- IUPAC Name: (1R)-1-(3-bromo-2-pyridyl)-2,2,2-trifluoro-ethanamine
- InChI: InChI=1S/C7H6BrF3N2/c8-4-2-1-3-13-5(4)6(12)7(9,10)11/h1-3,6H,12H2/t6-/m1/s1
- InChI Key: GCNHEWOOSWFSNT-ZCFIWIBFSA-N
- Exact Mass: 253.96665
- Molecular Formula: C7H6BrF3N2
- Molecular Weight: 255.03
- SMILES: C1=CC(=C(N=C1)[C@H](C(F)(F)F)N)Br
- Topological: 38.9
- Monoisotopic Mass: 253.96665
- Synonyms: (R)-1-(3-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHAN-1-AMINE, 1213066-11-5
(R)-1-(3-Bromopyridin-2-YL)-2,2,2-trifluoroethan-1-amine serves as a key chiral intermediate in the synthesis of pharmaceuticals, particularly for CNS-targeting drugs and enzyme inhibitors. Its bromopyridine group enables cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the trifluoroethylamine moiety enhances metabolic stability in drug design. Applications extend to agrochemical research for developing novel pesticides with improved enantioselectivity. The compound is also used in ligand design for asymmetric catalysis.
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