Description

Quinoline (CAS 91-22-5) is a heterocyclic aromatic organic compound with the molecular formula C₉H₇N. This colorless to slightly yellow liquid is characterized by its strong, distinct odor and is sparingly soluble in water but highly soluble in most organic solvents. Quinoline serves as a fundamental building block in medicinal chemistry, agrochemicals, and material science due to its versatile reactivity and structural properties. It is widely utilized as a precursor for the synthesis of antimalarial drugs, dyes, and corrosion inhibitors. Our high-purity Quinoline (>98%) is rigorously tested for quality, ensuring optimal performance in research and industrial applications. Available in various packaging options to suit laboratory and bulk-scale needs.

Properties

• CAS Number: 91-22-5
• Complexity: 111
• IUPAC Name: quinoline
• InChI: InChI=1S/C9H7N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-7H
• InChI Key: SMWDFEZZVXVKRB-UHFFFAOYSA-N
• LogP: log Kow= 2.03
• Exact Mass: 129.057849228
• Molecular Formula: C9H7N
• Molecular Weight: 129.16
• SMILES: C1=CC=C2C(=C1)C=CC=N2
• Topological: 12.9
• Monoisotopic Mass: 129.057849228
• Physical Description: Quinoline appears as a colorless liquid with a peculiar odor. Slightly denser than water. Contact may irritate to skin, eyes, and mucous membranes. May be toxic by ingestion. Used to make other chemicals.
• Color/Form: COLORLESS TO BROWN /SRP: TECHNICAL GRADE/
• Odor: Penetrating odor, not as offensive as pyridine
• Boiling Point: 460 °F at 760 mmHg
• Melting Point: 5 °F
• Flash Point: 138 °F
• Solubility: 12.4 [ug/mL]
• Density: 1.095 at 68 °F – Denser than water; will sink
• Vapor Density: 4.45 – Heavier than air; will sink
• Vapor Pressure: 1 mmHg at 139.5 °F ; 5 mmHg at 193.3 °F
• Stability/Shelf Life: DARKENS ON STORAGE IN ORDINARY, STOPPERED BOTTLE
• Autoignition Temperature: 896 °F
• Viscosity: 2.997 millipascal second at 30 °C
• Heat of Combustion: -8710 cal/g
• Surface Tension: 45.0 dynes/cm @ 20 °C
• Odor Threshold: Odor Threshold Low: 71.0 [ppm]
• Refractive Index: Index of refraction: 1.62683 @ 20 °C/D
• Dissociation Constants: pKa= 4.90
• Synonyms: QUINOLINE, 91-22-5, 1-Benzazine, 1-Azanaphthalene, Chinolin, Chinoleine, Chinoline, Quinolin, Leucol, Leukol, Benzopyridine, 2,3-Benzopyridine, Benzo(b)pyridine, Benzo[b]pyridine, Leucoline, USAF EK-218, 1-Benzine, FEMA No. 3470, B 500, CCRIS 547, NSC 3396, HSDB 121, DTXSID1021798, CHEBI:17362, AI3-01241, B-500, EINECS 202-051-6, UNII-E66400VT9R, E66400VT9R, NSC-3396, DTXCID401798, EC 202-051-6, QUINOLINE (IARC), QUINOLINE [IARC], 1-Benzazene, 1-AZANAPTHALENE, BENZO (B) PYRIDINE, 202-051-6, Quinoline-3-D, Quinoline-4-D, Quinoline-5-D, Quinoline-6-D, Quinoline-7-D, Quinoline-8-D, Quinoline (8CI,9CI), CHEMBL14474, 15793-82-5, 15793-83-6, 15793-84-7, 15793-85-8, 15793-86-9, 15793-87-0, Chinolin [Czech], Benzopyridine (VAN), Quinoline-, 4-quinolinyl, CAS-91-22-5, UN2656, hydroquinoline, Quinoline [UN2656] [Poison], MFCD00006736, MFCD31699982, MFCD31699983, MFCD31699984, MFCD31699985, MFCD31699986, MFCD31699987, Quinoline, >=97%, Quinoline, >=99%, QUINOLINE [MI], QUINOLINE [FHFI], QUINOLINE [HSDB], Quinoline > 90% grade, Epitope ID:140096, SCHEMBL2774, SCHEMBL2910, SCHEMBL8727, SCHEMBL8882, NCIOpen2_007906, SCHEMBL17830, SCHEMBL18329, SCHEMBL18594, SCHEMBL19695, SCHEMBL69131, WLN: T66 BNJ, MLS002303065, BIDD:ER0666, Quinoline, analytical standard, SCHEMBL101137, SCHEMBL131542, SCHEMBL196535, SCHEMBL198852, SCHEMBL448468, SCHEMBL449631, SCHEMBL449811, SCHEMBL450508, SCHEMBL451496, SCHEMBL451568, SCHEMBL451695, SCHEMBL451835, SCHEMBL451881, SCHEMBL451887, SCHEMBL452005, SCHEMBL452262, SCHEMBL452278, SCHEMBL452301, SCHEMBL452574, SCHEMBL454884, SCHEMBL1395756, SCHEMBL3130393, SCHEMBL6538293, SCHEMBL6538649, SCHEMBL7473305, Quinoline, reagent grade, 96%, Quinoline, reagent grade, 98%, FEMA 3470, NSC3396, Quinoline, redistilled from glass, DTXSID301317900, HMS2271F08, Quinoline [UN2656] [Poison], Quinoline, for synthesis, 96.0%, STR01546, Tox21_201478, Tox21_300068, BBL011390, BDBM50047015, s6369, SBB060379, STL146493, Quinoline 500 microg/mL in Methanol, AKOS000119139, UN 2656, NCGC00091190-01, NCGC00091190-02, NCGC00091190-03, NCGC00091190-04, NCGC00254119-01, NCGC00259029-01, Quinoline, SAJ first grade, >=94.0%, 54978-41-5, SMR000112309, SY246281, SY246329, SY246330, SY246331, SY246332, SY246333, Quinoline, JIS special grade, >=95.0%, DB-057248, NS00010850, Q0011, Q0085, ST51046569, EN300-19120, C06413, D97671, AE-641/01960007, Q408384, F0001-2218, Z104472852, InChI=1/C9H7N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-7, 31177-31-8

Application

Quinoline is extensively used as an intermediate in the synthesis of pharmaceuticals, particularly antimalarial agents such as chloroquine and quinine. It also serves as a key component in the production of dyes, fragrances, and pesticides. In material science, Quinoline derivatives are employed as corrosion inhibitors and chelating agents for metal ions. Its unique aromatic structure makes it valuable in organic synthesis and catalysis.

Safety and Hazards

GHS Hazard Statements

• H302: Harmful if swallowed [Warning Acute toxicity, oral]
• H311: Toxic in contact with skin [Danger Acute toxicity, dermal]
• H315: Causes skin irritation [Warning Skin corrosion/irritation]
• H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]
• H350: May cause cancer [Danger Carcinogenicity]
• H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
• H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
• H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
• H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P203, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute toxicity – Category 4
• Acute toxicity – Category 3
• Skin corrosion/irritation – Category 2
• Serious eye damage/eye irritation – Category 2A
• Germ cell mutagenicity – Category 2
• Carcinogenicity – Category 2
• Specific target organ toxicity – Single exposure – Category 2
• Specific target organ toxicity – Repeated exposure – Category 2 )
• Hazardous to the aquatic environment – Category 3
• Hazardous to the aquatic environment – Category 3

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.