Description

Description

Potassium ((propan-2-yloxy)methyl)trifluoroborate (CAS No. 1394048-67-9) is a highly specialized organoboron compound with the molecular formula C₄H₉BF₃KO. This potassium trifluoroborate salt is a valuable reagent in synthetic organic chemistry, particularly in cross-coupling reactions such as Suzuki-Miyaura couplings, where it serves as a stable and air-tolerant boronic acid surrogate. Its IUPAC name, potassium;trifluoro(propan-2-yloxymethyl)boranuide, reflects its precise structural configuration, featuring a propan-2-yloxymethyl group attached to a trifluoroborate anion. The compound is supplied as a high-purity solid, ensuring consistent performance in sensitive applications. Ideal for researchers and industrial chemists, this reagent is meticulously packaged under inert conditions to maintain stability and shelf life. Always handle with appropriate safety precautions, including the use of personal protective equipment (PPE) and adherence to standard laboratory protocols.

Application

Potassium ((propan-2-yloxy)methyl)trifluoroborate is widely used as a versatile building block in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. Its stability and reactivity make it a preferred choice for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds under mild conditions. This reagent is also employed in the preparation of boron-containing intermediates for materials science applications. Its compatibility with a range of solvents and catalysts enhances its utility in diverse synthetic workflows.

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