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Atomfair Potassium (1-boc-4-piperidinyloxy)methyltrifluoroborate C11H20BF3KNO3

Description Potassium (1-Boc-4-piperidinyloxy)methyltrifluoroborate (CAS No. 1364936-24-2) is a highly specialized organoboron reagent with the molecular formula C11H20BF3KNO3. This compound is an advanced synthetic intermediate, particularly valuable in cross-coupling reactions , peptide modifications , and medicinal chemistry applications. Its structure features a Boc-protected piperidinyloxy group coupled with a trifluoroborate moiety , offering enhanced stability and reactivity in Suzuki-Miyaura couplings. With a purity of ??95% (HPLC), this reagent is supplied as a white to off-white crystalline powder , ensuring consistent performance in sensitive reactions. Ideal for researchers in pharmaceutical development and organic synthesis , it is packaged under inert conditions to maintain…

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Description

Description

Potassium (1-Boc-4-piperidinyloxy)methyltrifluoroborate (CAS No. 1364936-24-2) is a highly specialized organoboron reagent with the molecular formula C11H20BF3KNO3. This compound is an advanced synthetic intermediate, particularly valuable in cross-coupling reactions, peptide modifications, and medicinal chemistry applications. Its structure features a Boc-protected piperidinyloxy group coupled with a trifluoroborate moiety, offering enhanced stability and reactivity in Suzuki-Miyaura couplings. With a purity of ??95% (HPLC), this reagent is supplied as a white to off-white crystalline powder, ensuring consistent performance in sensitive reactions. Ideal for researchers in pharmaceutical development and organic synthesis, it is packaged under inert conditions to maintain stability. Store at 2-8??C in a dry environment to prolong shelf life.

  • CAS No: 1364936-24-2
  • Molecular Formula: C11H20BF3KNO3
  • Molecular Weight: 321.19
  • Exact Mass: 321.1125396
  • Monoisotopic Mass: 321.1125396
  • IUPAC Name: potassium;trifluoro-[[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]oxymethyl]boranuide
  • SMILES: [B-](COC1CCN(CC1)C(=O)OC(C)(C)C)(F)(F)F.[K+]
  • Synonyms: 1364936-24-2, POTASSIUM (1-BOC-4-PIPERIDINYLOXY)METHYLTRIFLUOROBORATE, Potassium (((1-(tert-butoxycarbonyl)piperidin-4-yl)oxy)methyl)trifluoroborate, potassium [({1-[(tert-butoxy)carbonyl]piperidin-4-yl}oxy)methyl]trifluoroboranuide, potassium;trifluoro-[[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]oxymethyl]boranuide

Application

This reagent is primarily used in Suzuki-Miyaura cross-coupling reactions to introduce Boc-protected piperidinyloxy groups into complex molecules. It serves as a key intermediate in the synthesis of bioactive compounds and pharmaceutical candidates, particularly those targeting CNS disorders. Its trifluoroborate group enhances stability while maintaining reactivity under mild conditions.

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