Description

Description

Phenyl 4-fluorobenzenesulfonate (CAS No. 13656-61-6) is a high-purity sulfonate ester with the molecular formula C₁₂H₉FO₃S. This compound is characterized by its phenyl and 4-fluorophenyl groups linked via a sulfonate bridge, making it a valuable intermediate in organic synthesis and pharmaceutical research. It is supplied as a crystalline solid with exceptional purity (>98%) to ensure consistency in experimental results. Ideal for use in nucleophilic substitution reactions, cross-coupling methodologies, and as a precursor for advanced material synthesis. Suitable for researchers in medicinal chemistry, materials science, and chemical engineering. Store in a cool, dry place away from light and moisture to maintain stability.

Application

Phenyl 4-fluorobenzenesulfonate is widely utilized as a key intermediate in the synthesis of fluorinated aromatic compounds, particularly in pharmaceutical and agrochemical research. It serves as a versatile electrophile in nucleophilic aromatic substitution (S_NAr) reactions, enabling the introduction of fluorinated motifs into complex molecules. Researchers also employ it in polymer chemistry to modify sulfonate-containing monomers for advanced material applications. Its stability and reactivity make it a preferred choice for controlled functionalization in multi-step synthetic routes.

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