Description

Perfluoro-2-butyltetrahydrofuran (CAS No. 335-36-4) is a high-performance fluorinated solvent widely recognized for its exceptional chemical and thermal stability. With the molecular formula C₈F₁₆O, this perfluorinated compound exhibits outstanding inertness, making it ideal for demanding applications in research and industrial settings. Its unique properties include low surface tension, high dielectric strength, and excellent compatibility with sensitive materials. Commonly referred to as Fluorinert FC-75, this product is available in rigorously controlled batches to ensure consistency and reliability for critical processes. Suitable for use in electronics cooling, heat transfer fluids, and as a reaction medium in synthetic chemistry.

Properties

• CAS Number: 335-36-4
• Complexity: 545
• IUPAC Name: 2,2,3,3,4,4,5-heptafluoro-5-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)tetrahydrofuran
• InChI: InChI=1S/C8F16O/c9-1(10,4(15,16)7(20,21)22)2(11,12)6(19)3(13,14)5(17,18)8(23,24)25-6
• InChI Key: FYJQJMIEZVMYSD-UHFFFAOYSA-N
• Exact Mass: 415.9693652
• Molecular Formula: C8F16O
• Molecular Weight: 416.06
• SMILES: C1(C(C(OC1(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)F)(F)F)(F)F)(F)F
• Topological: 9.2
• Monoisotopic Mass: 415.9693652
• Physical Description: Liquid
• Synonyms: Perfluoro-2-butyltetrahydrofuran, 335-36-4, Fluorinert FC 75, 2,2,3,3,4,4,5-heptafluoro-5-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)oxolane, MSL8VN7XHA, Furan, 2,2,3,3,4,4,5-heptafluorotetrahydro-5-(nonafluorobutyl)-, 2,2,3,3,4,4,5-Heptafluorotetrahydro-5-(nonafluorobutyl)furan, 2,2,3,3,4,4,5-heptafluoro-5-(nonafluorobutyl)tetrahydrofuran, CHEBI:39023, DTXSID60871632, FC-75, RM101, 2,2,3,3,4,4,5-HEPTAFLUOROTETRAHYDRO-5-(1,1,2,2,3,3,4,4,4-NONAFLUOROBUTYL)FURAN, Furan, 2,2,3,3,4,4,5-heptafluorotetrahydro-5-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)-, Perfluoro(2nbutyltetrahydrofuran), DTXCID70819282, Heptafluorotetrahydro2(nonafluorobutyl)furan, Furan, heptafluorotetrahydro2(nonafluorobutyl), 2,2,3,3,4,4,5Heptafluorotetrahydro5(nonafluorobutyl)furan, Furan, 2,2,3,3,4,4,5heptafluorotetrahydro5(nonafluorobutyl), Furan, 2,2,3,3,4,4,5heptafluorotetrahydro5(1,1,2,2,3,3,4,4,4nonafluorobutyl), 206-389-5, Heptafluorotetrahydro(nonafluorobutyl)furan, 40464-54-8, Perfluoro(2-butyltetrahydrofuran), spectrasynq pfbthf, 11072-16-5, FC 75, MFCD00014513, FC75, Heptafluorotetrahydro-2-(nonafluorobutyl)furan, Furan, heptafluorotetrahydro(nonafluorobutyl)-, Furan, heptafluorotetrahydro-2-(nonafluorobutyl)-, fluorinert fc-75, perfluoro-compound fc-75, Fluorocarbon 77, EINECS 206-389-5, EINECS 254-933-5, fluorinert(r) fc-75, UNII-MSL8VN7XHA, 2-Nonafluorobutyl-heptafluorotetrahydrofuran, SCHEMBL63047, fluorinert(tm) (fc-75)(r), fluorinert ™ (fc-75) (reg), perfluoro-2-n-butyltetrahydrofurane, exadecafluoro-2-butyltetrahydrofuran, perfluoro(2-n-butyltetrahydrofuran), AKOS005063731, FP60439, NS00011165, NS00112221, D92031, perfluoro-2-butyltetrahydrofuran fc-75 mixture, Perfluoro-2-butyltetrahydrofuran, mixture of isomers, Q5424695, Perfluoro-2-n-butyltetrahydrofurane (mixture of isomers)

Perfluoro-2-butyltetrahydrofuran is extensively used as a heat transfer fluid in electronic cooling systems due to its thermal stability and dielectric properties. It serves as an inert solvent in synthetic chemistry, particularly for reactions involving highly reactive or oxygen-sensitive compounds. Additionally, its low surface tension and biocompatibility make it valuable in medical device testing and as a component in contrast agents for imaging applications.

Safety and Hazards

GHS Hazard Statements

• H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H413 (50%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (50%)
• Eye Irrit. 2 (50%)
• STOT SE 3 (50%)
• Aquatic Chronic 4 (50%)

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