Description

Description

p-(Trifluoromethoxy)phenyl isocyanate (CAS No. 35037-73-1) is a high-purity aromatic isocyanate compound with the molecular formula C₈H₄F₃NO₂. This specialized chemical is widely utilized in organic synthesis, pharmaceuticals, and advanced material research due to its reactive isocyanate functional group and trifluoromethoxy substituent. The compound is characterized by its clear to pale yellow appearance and should be stored under inert conditions to prevent moisture absorption and degradation. With an IUPAC name of 1-isocyanato-4-(trifluoromethoxy)benzene, it is a valuable building block for ureas, carbamates, and other nitrogen-containing heterocycles. Our product is rigorously tested for purity and consistency, ensuring optimal performance in sensitive applications. Available in various quantities, it is packaged in sealed glass containers under nitrogen to maintain stability.

Application

p-(Trifluoromethoxy)phenyl isocyanate is primarily used as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty polymers. Its reactive isocyanate group enables facile conjugation with amines and alcohols to form ureas and carbamates, respectively. The trifluoromethoxy moiety enhances lipophilicity and metabolic stability, making it valuable in drug discovery. Additionally, it serves as a crosslinking agent in polyurethane and polyurea coatings, contributing to durability and chemical resistance. Researchers also employ it in the development of advanced materials with tailored surface properties.

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