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Atomfair p-Fluorobenzaldehyde 4-Fluorobenzaldehyde C7H5FO CAS 459-57-4

p-Fluorobenzaldehyde is a high-purity aromatic aldehyde widely utilized in organic synthesis and pharmaceutical research. This compound, with the molecular formula C7H5FO , serves as a versatile building block for the preparation of fluorinated intermediates and active pharmaceutical ingredients (APIs). Its distinct fluorinated aromatic structure enhances reactivity in nucleophilic substitution and condensation reactions, making it invaluable in fine chemical synthesis. Supplied as a clear to pale-yellow liquid, p-Fluorobenzaldehyde is rigorously tested to meet stringent quality standards, ensuring optimal performance in sensitive applications. It is compatible with a broad range of solvents, including ethanol, methanol, and dichloromethane, facilitating easy integration into synthetic…

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Description

p-Fluorobenzaldehyde is a high-purity aromatic aldehyde widely utilized in organic synthesis and pharmaceutical research. This compound, with the molecular formula C7H5FO, serves as a versatile building block for the preparation of fluorinated intermediates and active pharmaceutical ingredients (APIs). Its distinct fluorinated aromatic structure enhances reactivity in nucleophilic substitution and condensation reactions, making it invaluable in fine chemical synthesis.

Supplied as a clear to pale-yellow liquid, p-Fluorobenzaldehyde is rigorously tested to meet stringent quality standards, ensuring optimal performance in sensitive applications. It is compatible with a broad range of solvents, including ethanol, methanol, and dichloromethane, facilitating easy integration into synthetic workflows. Proper storage under inert conditions is recommended to maintain stability and prevent degradation.

This product is ideal for researchers developing fluorinated compounds for agrochemicals, dyes, and advanced materials. Its consistent quality and reliable reactivity make it a preferred choice for academic, industrial, and pharmaceutical laboratories.

Properties

  • CAS Number: 459-57-4
  • Complexity: 95.1
  • IUPAC Name: 4-fluorobenzaldehyde
  • InChI: InChI=1S/C7H5FO/c8-7-3-1-6(5-9)2-4-7/h1-5H
  • InChI Key: UOQXIWFBQSVDPP-UHFFFAOYSA-N
  • Exact Mass: 124.032442941
  • Molecular Formula: C7H5FO
  • Molecular Weight: 124.11
  • SMILES: C1=CC(=CC=C1C=O)F
  • Topological: 17.1
  • Monoisotopic Mass: 124.032442941
  • Synonyms: 4-Fluorobenzaldehyde, 459-57-4, p-Fluorobenzaldehyde, Benzaldehyde, 4-fluoro-, Benzaldehyde, p-fluoro-, DTXSID0038756, NSC-68095, N8681893GA, DTXCID8018756, 207-293-6, para-Fluorobenzaldehyde, 4-flurobenzaldehyde, 4-fluoro-benzaldehyde, MFCD00003378, CHEMBL3183207, p-fluorbenzaldehyde, UNII-N8681893GA, 4fluorobenzaldehyde, 4-fluorobenzaldehyd, 4-fluorobenzaldehye, 4-fluorobenzaldeyde, 4-fluorobezaldehyde, 4-Fluorobenzaldhyde, EINECS 207-293-6, 4-floro benzaldehyde, 4-fluor-benzaldehyde, NSC 68095, p-fluoro benzaldehyde, p-fluoro-benzaldehyde, rho-Fluorobenzaldehyde, 4-flouro benzaldehyde, 4-flourobenzenaldehyde, 4-fluoro benzaldehyde, 4-fluorobenz aldehyde, 4-fluorobenz-aldehyde, 4-fluorobenzenaldehyde, 4-fluoro-benzaldehy-de, para-fluoro benzaldehyde, (4-fluorophenyl)methanone, SCHEMBL2964, p-Fluorobenzenecarboxaldehyde, 4-Fluorobenzaldehyde, 98%, SCHEMBL96826, SCHEMBL15066847, SCHEMBL15067306, BCP26576, HY-Y0197, NSC68095, Tox21_302122, BDBM50234267, SBB040209, STK801571, AKOS000118950, AC-2504, CS-W008729, FF10306, PS-9210, NCGC00255446-01, CAS-459-57-4, DB-024090, F0191, NS00043587, ST50213354, EN300-19137, 4-Fluorobenzaldehyde(Discontinued,See C4X-1132112), Q27284696, F2190-0627, Z104472914, NSC 68095; p-Fluorobenzaldehyde; p-Fluorobenzenecarboxaldehyde;, p-Fluorobenzaldehyde pound>>Benzaldehyde, 4-fluoro- pound>>4-Fluoro-benzaldehyde

p-Fluorobenzaldehyde is extensively used as a key intermediate in the synthesis of fluorinated pharmaceuticals, including antifungal and anti-inflammatory agents. Its electron-withdrawing fluorine group enhances the electrophilicity of the aldehyde, enabling efficient participation in Grignard reactions, reductive amination, and Knoevenagel condensations. In material science, it serves as a precursor for fluorinated liquid crystals and polymers with tailored optical properties. Additionally, it finds utility in agrochemical research for developing novel pesticides and herbicides.

Safety and Hazards

GHS Hazard Statements

  • H226: Flammable liquid and vapor [Warning Flammable liquids]

Precautionary Statements

  • P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501

Hazard Classes and Categories

  • Flam. Liq. 3 (82.4%)
  • Acute Tox. 4 (24.3%)
  • Skin Irrit. 2 (74.3%)
  • Eye Irrit. 2A (90.5%)
  • STOT SE 3 (70.3%)
  • Aquatic Chronic 2 (23%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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