Description

o-Toluohydrazide (CAS No. 7658-80-2) is a high-purity organic compound with the molecular formula C₈H₁₀N₂O, widely utilized in pharmaceutical and chemical research. This white to off-white crystalline solid, also known as 2-methylbenzohydrazide, exhibits excellent stability under standard laboratory conditions. With a molecular weight of 150.18 g/mol, it serves as a versatile intermediate in heterocyclic synthesis and medicinal chemistry applications. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied in securely sealed packaging to maintain integrity. Ideal for researchers developing novel hydrazide-based compounds, this reagent is a critical building block for the synthesis of biologically active molecules, including potential anticancer and antimicrobial agents. Store in a cool, dry place away from strong oxidizing agents.

Properties

• CAS Number: 7658-80-2
• Complexity: 147
• IUPAC Name: 2-methylbenzohydrazide
• InChI: InChI=1S/C8H10N2O/c1-6-4-2-3-5-7(6)8(11)10-9/h2-5H,9H2,1H3,(H,10,11)
• InChI Key: KFXLXEQCRFGDRU-UHFFFAOYSA-N
• Exact Mass: 150.079312947
• Molecular Formula: C8H10N2O
• Molecular Weight: 150.18
• SMILES: CC1=CC=CC=C1C(=O)NN
• Topological: 55.1
• Monoisotopic Mass: 150.079312947
• Synonyms: 2-Methylbenzohydrazide, 7658-80-2, o-Toluic hydrazide, o-Toluic acid hydrazide, 2-Toluic hydrazide, o-Toluohydrazide, 2-Methylbenzoic acid hydrazide, 6CDR3O391Q, O-TOLUOYLHYDRAZINE, 2-TOLUOYLHYDRAZINE, EINECS 231-623-8, NSC 61566, NSC-61566, UNII-6CDR3O391Q, AI3-32878, O-METHYLBENZOYL HYDRAZIDE, O-TOLUIC ACID, HYDRAZIDE, 2-METHYLBENZOIC HYDRAZIDE, (O-METHYLBENZOYL)HYDRAZINE, DTXSID30227384, (2-METHYLBENZOYL)HYDRAZINE, 2-METHYLBENZOCARBOHYDRAZIDE, O-METHYLBENZOIC ACID HYDRAZIDE, 2-METHYLBENZENECARBOXYLIC ACID HYDRAZIDE, DTXCID30149875, 231-623-8, kfxlxeqcrfgdru-uhfffaoysa-n, 2-Methyl-benzoic acid hydrazide, Benzoic acid, 2-methyl-, hydrazide, MFCD00014756, 2-methylbenzenecarbohydrazide, o-toluic hydrazine, methylbenzohydrazide, 2-Methylbenzohydrazide #, SCHEMBL1128274, SCHEMBL10587935, SCHEMBL11419106, NSC61566, BBL008111, SBB028289, STK009886, AKOS000194934, FT05302, GS-3017, SB85979, SY061982, 2-Methylbenzohydrazide, o-Toluic hydrazide, DB-056090, CS-0096270, NS00037812, ST45035276, EN300-16650, H11322, Z56347320

Application

o-Toluohydrazide is primarily employed as a key synthetic intermediate in the preparation of heterocyclic compounds such as indazoles and benzotriazines. Researchers utilize this compound in medicinal chemistry for the development of hydrazide-based pharmacophores with potential therapeutic applications. It also serves as a precursor in the synthesis of Schiff base ligands for coordination chemistry studies. Additionally, o-toluohydrazide finds use in polymer science as a modifying agent for specialty resins.

Safety and Hazards

GHS Hazard Statements

• H301 (25%): Toxic if swallowed [Danger Acute toxicity, oral]
• H311 (25%): Toxic in contact with skin [Danger Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H331 (25%): Toxic if inhaled [Danger Acute toxicity, inhalation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (25%)
• Acute Tox. 3 (25%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• Acute Tox. 3 (25%)
• STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.