Description

Nuarimol (CAS No. 63284-71-9), with the molecular formula C₁₇H₁₂ClFN₂O, is a highly effective systemic fungicide widely used in agricultural and horticultural applications. This compound belongs to the pyrimidine class of fungicides, known for their broad-spectrum activity against various fungal pathogens. Nuarimol is particularly effective in controlling powdery mildews, rusts, and other foliar diseases in crops such as cereals, fruits, and vegetables. Its unique mode of action involves inhibition of ergosterol biosynthesis, disrupting fungal cell membrane integrity and leading to cell death.

Available in various formulations including wettable powders, emulsifiable concentrates, and soluble concentrates, Nuarimol is compatible with integrated pest management (IPM) programs. It is also used as an analytical standard in research and quality control laboratories. With its proven efficacy and reliability, Nuarimol remains a trusted choice for researchers and agricultural professionals seeking robust fungal disease management solutions.

Properties

• CAS Number: 63284-71-9
• Complexity: 359
• IUPAC Name: (2-chlorophenyl)-(4-fluorophenyl)-pyrimidin-5-yl-methanol
• InChI: InChI=1S/C17H12ClFN2O/c18-16-4-2-1-3-15(16)17(22,13-9-20-11-21-10-13)12-5-7-14(19)8-6-12/h1-11,22H
• InChI Key: SAPGTCDSBGMXCD-UHFFFAOYSA-N
• Exact Mass: 314.0622189
• Molecular Formula: C17H12ClFN2O
• Molecular Weight: 314.7
• SMILES: C1=CC=C(C(=C1)C(C2=CC=C(C=C2)F)(C3=CN=CN=C3)O)Cl
• Topological: 46
• Monoisotopic Mass: 314.0622189
• Synonyms: Nuarimol, Trimidal, Nuarimol [ISO], Nuarimol [ANSI:BSI:ISO], 5-(2-Chloro-4′-fluorobenzhydryl)-4-hydroxypyrimidine, Gauntlet, Tridal, UNII-ZU7K80U0CY, EINECS 264-071-1, ZU7K80U0CY, EPA Pesticide Chemical Code 224100, BRN 6223667, Cidorel (Salt/Mix), DTXSID2042220, Gandural (Salt/Mix), (.+/-.)-Nuarimol, 5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-fluorophenyl)-, DTXCID0022220, (+-)-2-Chloro-4′-fluoro-alpha-(pyrimidin-5-yl)benzhydryl alcohol, 5-Pyrimidinemethanol, .alpha.-(2-chlorophenyl)-.alpha.-(4-fluorophenyl)-, DNDI1255614, EL-2289, (2-chlorophenyl)-(4-fluorophenyl)-pyrimidin-5-yl-methanol, Nuarimol (ANSI:BSI:ISO), 2-Chloro-4′-fluoro-.alpha.-(pyrimidin-5-yl)benzhydryl alcohol, (.+/-.)-2-Chloro-4′-fluoro-.alpha.-(pyrimidin-5-yl)benzhydryl alcohol, Trimifruit, rac-nuarimol, (+-)-nuarimol, CHEBI:7645, alpha-(2-chlorophenyl)-alpha-(4-fluorophenyl)-5-pyrimidine methanol, rac-(2-chlorophenyl)(4-fluorophenyl)pyrimidin-5-ylmethanol, 2-Chloro-4′-fluoro-alpha-(pyrimidin-5-yl)benzhydryl alcohol, (rs)-2-chloro-4′-fluoro-alpha-(pyrimidin-5-yl)benzhydryl alcohol, rac-(R)-(2-chlorophenyl)(4-fluorophenyl)(pyrimidin-5-yl)methanol, 5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-fluorophenyl)-(9CI), (rs)-(2-chlorophenyl)(4-fluorophenyl)(pyrimidin-5-yl)methanol, sapgtcdsbgmxcd-uhfffaoysa-n, 63284-71-9, Guantlet, Triminol, Murox, Trimifruit SC, EL 228, EL 2289, Nuarimol 10 microg/mL in Cyclohexane, Caswell No. 419G, 2-Chloro-4′-fluoro-alpha-(pyrimidin-5-yl)diphenylmethanol, alpha-(2-Chlorophenyl)-alpha-(4-fluorophenyl)-5-pyrimidinemethanol, SCHEMBL20691, (+/-)-NUARIMOL, CHEMBL1863087, (2-chlorophenyl)-(4-fluorophenyl)-pyrimidin-5-ylmethanol, MSK20336, Tox21_301251, NCGC00255760-01, CAS-63284-71-9, NS00002335, Nuarimol, PESTANAL(R), analytical standard, Q15632816, (2-Chlorophenyl)(4-fluorophenyl)5-pyrimidinylmethanol #, 2-Chloro-4′-fluoro-.alpha.-(pyrimidin-5-yl)diphenylmethanol, .alpha.-(2-Chlorophenyl)-.alpha.-(4-fluorophenyl)-5-pyrimidinemethanol

Nuarimol is primarily used as a systemic fungicide to control powdery mildew, rusts, and other fungal diseases in cereals, fruits, and vegetables. It is applied as a foliar spray or seed treatment, providing long-lasting protection against fungal infections. The compound is also utilized in research settings as a reference standard for analytical and environmental studies. Its ergosterol biosynthesis inhibition mechanism makes it a valuable tool in studying fungal resistance and mode of action.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Eye Irrit. 2 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.