Description

Noopept (GVS-111, Omberacetam) is a highly potent synthetic nootropic peptide with the molecular formula C₁₇H₂₂N₂O₄ and CAS number 157115-85-0. Its IUPAC name is ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate. This neuroprotective compound exhibits cognitive-enhancing properties at significantly lower doses (1000x more potent than piracetam) due to its unique mechanism of action, modulating glutamate and acetylcholine receptors while stimulating NGF and BDNF expression. Noopept is supplied as a high-purity (>98%) white crystalline powder, soluble in DMSO and ethanol but poorly soluble in water. Suitable for research applications in neuroscience, neuropharmacology, and cognitive studies. Store at -20°C protected from light and moisture.

Properties

• CAS Number: 157115-85-0
• Complexity: 432
• IUPAC Name: ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate
• InChI: InChI=1S/C17H22N2O4/c1-2-23-16(21)12-18-17(22)14-9-6-10-19(14)15(20)11-13-7-4-3-5-8-13/h3-5,7-8,14H,2,6,9-12H2,1H3,(H,18,22)/t14-/m0/s1
• InChI Key: PJNSMUBMSNAEEN-AWEZNQCLSA-N
• Exact Mass: 318.15795719
• Molecular Formula: C17H22N2O4
• Molecular Weight: 318.4
• SMILES: CCOC(=O)CNC(=O)[C@@H]1CCCN1C(=O)CC2=CC=CC=C2
• Topological: 75.7
• Monoisotopic Mass: 318.15795719
• Synonyms: Noopept, 157115-85-0, GVS-111, Omberacetam, n-phenylacetyl-l-prolylglycine ethyl ester, Glycine, 1-(phenylacetyl)-L-prolyl-, ethyl ester, ethyl phenylacetyl-Pro-Gly, 4QBJ98683M, OMBERACETAM [INN], Glycine, N-(1-(phenylacetyl)-L-prolyl)-, ethyl ester, DTXSID80166214, DVD-111, J759.455K, omberacetamum, NOOPEPT [WHO-DD], DTXCID0088705, 1-(2-Phenylacetyl)-L-prolylglycine ethy ester, 839-170-3, (S)-Ethyl 2-(1-(2-phenylacetyl)pyrrolidine-2-carboxamido)acetate, ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate, Glycine, 1-(2-phenylacetyl)-L-prolyl-, ethyl ester, N-(1-(Phenylacetyl)-L-prolyl)glycine ethyl ester, ethyl (2-phenylacetyl)-L-prolylglycinate, 1-(2-phenylacetyl)-l-prolylglycine ethyl ester, GVS 111, N-[1-(Phenylacetyl)-L-prolyl]glycine Ethyl Ester, N-Phenylacetyl-L-prolylglycine ethyl ester;SGS 111, SGS-111, UNII-4QBJ98683M, ethyl 2-{[(2S)-1-(2-phenylacetyl)pyrrolidin-2-yl]formamido}acetate, Omberacetam (Standard), ethyl 1-(phenylacetyl)-L-prolylglycinate, Omberacetam [WHO-DD], Noopept – Bio-X trade mark, SCHEMBL194807, Noopept, >=98% (HPLC), CHEMBL4303687, GLXC-04495, HY-17456R, AKOS016012268, CS-1575, NCGC00378939-05, AS-10555, BN300104, FN138082, HY-17456, DB-371006, N1120, NS00017406, Ethyl N-[1-(Phenylacetyl)-L-prolyl]glycinate, C72975, Q7049784, BRD-K22520627-001-01-7

Application

Noopept is widely studied for its neuroprotective and cognitive-enhancing effects in experimental models. Research indicates potential applications in memory enhancement, neuroprotection against oxidative stress, and modulation of neurotransmitter systems. The compound shows particular promise in studies of age-related cognitive decline and neurodegenerative conditions. Its unique pharmacokinetic profile allows for investigation of blood-brain barrier penetration mechanisms.

Safety and Hazards

GHS Hazard Statements

• Not Classified
• Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website.

Hazard Classes and Categories

• Not Classified

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.