Description

Nicotinic Acid Hydrazide (CAS No. 553-53-7), also known as pyridine-3-carbohydrazide, is a high-purity biochemical reagent with the molecular formula C₆H₇N₃O. This compound is widely utilized in pharmaceutical research, organic synthesis, and as a precursor for the development of hydrazide-based derivatives. Its well-defined structure and reactivity make it an essential building block for medicinal chemistry applications, particularly in the synthesis of antitubercular and antimicrobial agents. Available in various quantities, our Nicotinic Acid Hydrazide is rigorously tested for quality, ensuring optimal performance in your laboratory workflows. Store in a cool, dry place to maintain stability and longevity.

Properties

• CAS Number: 553-53-7
• Complexity: 126
• IUPAC Name: pyridine-3-carbohydrazide
• InChI: InChI=1S/C6H7N3O/c7-9-6(10)5-2-1-3-8-4-5/h1-4H,7H2,(H,9,10)
• InChI Key: KFUSANSHCADHNJ-UHFFFAOYSA-N
• Exact Mass: 137.058911855
• Molecular Formula: C6H7N3O
• Molecular Weight: 137.14
• SMILES: C1=CC(=CN=C1)C(=O)NN
• Topological: 68
• Monoisotopic Mass: 137.058911855
• Synonyms: Nicotinohydrazide, Nicotinic acid hydrazide, 553-53-7, pyridine-3-carbohydrazide, Niazid, 3-Pyridylcarbonylhydrazine, NICOTINIC ACID, HYDRAZIDE, CCRIS 1374, UNII-AF1LLO72TM, AF1LLO72TM, Nicotinylhydrazine, Nicotinoylhydrazine, EINECS 209-041-0, Nicotinyl hydrazide, 3-Pyridoylhydrazine, DTXSID6020933, AI3-17494, NSC-18775, NSC-36088, 3-Pyridinecarboxylic hydrazide, DTXCID40933, ISONIAZID IMPURITY D [EP IMPURITY], ISONIAZID IMPURITY D (EP IMPURITY), inchi=1/c6h7n3o/c7-9-6(10)5-2-1-3-8-4-5/h1-4h,7h2,(h,9,10, kfusanshcadhnj-uhfffaoysa-n, n’-(2-methyl-3-phenylallylidene)nicotinohydrazide monohydrate, n’-(3-phenylallylidene)nicotinohydrazide monohydrate, Nicotinic hydrazide, Nicotinylhydrazide, Nicotinoyl hydrazine, 3-Pyridoyl hydrazine, 3-Pyridinecarboxylic acid, hydrazide, Nicotinoyl hydrazide, Hydrazine, nicotinoyl-, (3-Pyridylcarbonyl)hydrazine, WS 102, NSC 36088, NSC 18775, 3-Isoniazid, 3-pyridinecarbohydrazide, MFCD00006383, WLN: T6NJ CVMZ, NSC18775, NSC36088, NicotinicHydrazide, 3-Pyridinecarboxylic acid hydrazide, nicotinic acid hydrazone, Nicotinic hydrazide, 97%, SCHEMBL258390, pyridine, 3-hydrazinocarbonyl-, CHEMBL124495, SCHEMBL10896904, SCHEMBL11732038, 3-Pyridinecarboxamide, 2′-amino-, ALBB-025730, NSC41703, STR00999, pyridine-3-carboxylic acid hydrazide, Tox21_200666, BBL003565, NSC-41703, SBB028255, STK034751, AKOS000119627, BS-3780, CS-W013333, FI24684, HY-W012617, NCGC00248790-01, NCGC00258220-01, CAS-553-53-7, SY033050, DB-052717, N0087, NS00033298, ST45028835, EN300-18499, F16329, M02155, A830602, Nicotinic hydrazide, Vetec(TM) reagent grade, 97%, Q27273901, Z58981809, F0001-1451, Nicotinic acid hydrazide;Nicotinohydrazide;3-Pyridinecarboxylic acid hydrazide

Application

Nicotinic Acid Hydrazide is primarily used in pharmaceutical research as a key intermediate for synthesizing hydrazide derivatives with potential antitubercular and antimicrobial properties. It serves as a versatile reagent in organic synthesis, enabling the formation of heterocyclic compounds. Researchers also employ it in the development of novel therapeutic agents due to its ability to modulate biological activity. Its applications extend to material science, where it acts as a ligand or chelating agent in coordination chemistry.

Safety and Hazards

GHS Hazard Statements

• H315 (89.6%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (91.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (87.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H351 (10.4%): Suspected of causing cancer [Warning Carcinogenicity]

Precautionary Statements

• P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (89.6%)
• Eye Irrit. 2 (91.7%)
• STOT SE 3 (87.5%)
• Carc. 2 (10.4%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.