Atomfair N-methyl-N-[(trimethylsilyl)oxy]methanesulfonamide C5H15NO3SSi CAS 2376523-30-5

N-methyl-N-[(trimethylsilyl)oxy]methanesulfonamide (CAS No. 2376523-30-5) is a high-purity organosilicon compound with the molecular formula C5H15NO3SSi . This specialized reagent is designed for advanced synthetic applications, featuring a unique combination of a sulfonamide group and a trimethylsilyloxy moiety. The compound is characterized by its exceptional stability and reactivity, making it an invaluable tool for researchers working in organic synthesis, medicinal chemistry, and materials science. Available in rigorously controlled batches with ≥95% purity (GC), it is supplied in amber glass vials under inert atmosphere to ensure maximum shelf life. Technical specifications include: molecular weight 197.34 g/mol, density 1.08 g/cm3, and storage recommendations of…

Description

N-methyl-N-[(trimethylsilyl)oxy]methanesulfonamide (CAS No. 2376523-30-5) is a high-purity organosilicon compound with the molecular formula C5H15NO3SSi. This specialized reagent is designed for advanced synthetic applications, featuring a unique combination of a sulfonamide group and a trimethylsilyloxy moiety. The compound is characterized by its exceptional stability and reactivity, making it an invaluable tool for researchers working in organic synthesis, medicinal chemistry, and materials science. Available in rigorously controlled batches with ≥95% purity (GC), it is supplied in amber glass vials under inert atmosphere to ensure maximum shelf life. Technical specifications include: molecular weight 197.34 g/mol, density 1.08 g/cm3, and storage recommendations of 2-8°C under argon. MSDS and analytical certificates are available upon request.

Properties

  • CAS Number: 2376523-30-5
  • Complexity: 213
  • IUPAC Name: N-methyl-N-trimethylsilyloxy-methanesulfonamide
  • InChI: InChI=1S/C5H15NO3SSi/c1-6(10(2,7)8)9-11(3,4)5/h1-5H3
  • InChI Key: VIXCQQUPBLWAMV-UHFFFAOYSA-N
  • Exact Mass: 197.05419105
  • Molecular Formula: C5H15NO3SSi
  • Molecular Weight: 197.33
  • SMILES: CN(O[Si](C)(C)C)S(=O)(=O)C
  • Topological: 55
  • Monoisotopic Mass: 197.05419105
  • Synonyms: SCHEMBL21352294, DB-159729, N-methyl-N-[(trimethylsilyl)oxy]methanesulfonamide, 2376523-30-5

Application

This compound serves as a versatile building block in organic synthesis, particularly for the introduction of protected sulfonamide functionalities. It finds application in the preparation of advanced pharmaceutical intermediates where selective N-protection is required. Researchers utilize it in nucleophilic substitution reactions and as a precursor for silicon-based protecting group strategies. The trimethylsilyloxy group offers enhanced stability during multi-step synthetic sequences while maintaining good leaving group properties.

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Disclaimer

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