Description

N-Ethylnicotinamide (CAS No. 4314-66-3) is a high-purity organic compound with the molecular formula C₈H₁₀N₂O, widely utilized in pharmaceutical and biochemical research. This derivative of nicotinamide features an ethyl group substitution on the amide nitrogen, enhancing its solubility and reactivity profile. With an IUPAC name of N-ethylpyridine-3-carboxamide, it serves as a versatile intermediate in the synthesis of bioactive molecules, enzyme inhibitors, and metabolic modulators. Our product is rigorously tested to ensure ≥98% purity (HPLC/GC), making it ideal for precision applications in drug discovery, medicinal chemistry, and enzymatic studies. Available in crystalline powder form, it is packaged under inert conditions to guarantee stability and longevity.

Key Features:

• CAS: 4314-66-3
• Molecular Weight: 150.18 g/mol
• Purity: ≥98% (HPLC/GC)
• Synonyms: 3-Pyridinecarboxamide, N-ethyl-; Nicotinic acid monoethylamide

Properties

• CAS Number: 4314-66-3
• Complexity: 136
• IUPAC Name: N-ethylpyridine-3-carboxamide
• InChI: InChI=1S/C8H10N2O/c1-2-10-8(11)7-4-3-5-9-6-7/h3-6H,2H2,1H3,(H,10,11)
• InChI Key: ZXOAHASJYIUCBG-UHFFFAOYSA-N
• Exact Mass: 150.079312947
• Molecular Formula: C8H10N2O
• Molecular Weight: 150.18
• SMILES: CCNC(=O)C1=CN=CC=C1
• Topological: 42
• Monoisotopic Mass: 150.079312947
• Synonyms: N-Ethylnicotinamide, 4314-66-3, 3-Pyridinecarboxamide, N-ethyl-, Nicotinamide, N-ethyl-, Nicotinic acid monoethylamide, N-Ethyl-3-pyridinecarboxamide, N-Monoethylnicotinamide, Nicotinic acid ethylamide, EINECS 224-331-7, NSC 62008, BRN 0122945, 1G18T31MNW, NSC-62008, ETHYLNICOTINAMIDE, N-, DTXSID10195719, 5-22-02-00083 (Beilstein Handbook Reference), DTXCID00118210, 3-Pyridinecarboxamide, N-ethyl-(9CI), 224-331-7, N-ethylpyridine-3-carboxamide, N-ethyl nicotinamide, MFCD00023579, UNII-1G18T31MNW, Oprea1_347767, SCHEMBL353230, SCHEMBL1233991, SCHEMBL3725252, SCHEMBL23036848, ZXOAHASJYIUCBG-UHFFFAOYSA-, NSC62008, AKOS003865635, SB76319, BS-17256, DB-051037, CS-0151981, E0150, NS00031308, D82018, InChI=1/C8H10N2O/c1-2-10-8(11)7-4-3-5-9-6-7/h3-6H,2H2,1H3,(H,10,11)

Application

N-Ethylnicotinamide is primarily employed as a precursor in the synthesis of nicotinamide-based pharmaceuticals, including potential NAD+ modulators. Researchers leverage its structural properties to investigate enzyme inhibition, particularly in studies targeting sirtuins and other NAD+-dependent proteins. It also finds use in metabolic pathway analysis due to its role as a nicotinamide analog, aiding in the exploration of vitamin B3 derivatives.

Safety and Hazards

GHS Hazard Statements

• H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501

Hazard Classes and Categories

• Acute Tox. 4 (97.5%)
• Eye Irrit. 2 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.