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Atomfair N-(2,2,2-Trifluoroethyl)thiophene-2-sulfonamide C6H6F3NO2S2 CAS 2326993-78-4

N-(2,2,2-Trifluoroethyl)thiophene-2-sulfonamide (CAS No. 2326993-78-4) is a high-purity sulfonamide derivative designed for advanced research and industrial applications. With the molecular formula C6H6F3NO2S2, this compound features a thiophene-2-sulfonamide backbone coupled with a reactive 2,2,2-trifluoroethyl group, making it a valuable intermediate in medicinal chemistry, agrochemical synthesis, and materials science. Its unique trifluoroethyl moiety enhances electrophilicity and metabolic stability, ideal for probing structure-activity relationships (SAR) or developing fluorinated bioactive molecules. Packaged under inert conditions to ensure stability, this product is rigorously tested via HPLC, NMR, and mass spectrometry to meet ≥95% purity standards. Suitable for use in cross-coupling reactions, sulfonylation protocols, and as a…

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Description

N-(2,2,2-Trifluoroethyl)thiophene-2-sulfonamide (CAS No. 2326993-78-4) is a high-purity sulfonamide derivative designed for advanced research and industrial applications. With the molecular formula C6H6F3NO2S2, this compound features a thiophene-2-sulfonamide backbone coupled with a reactive 2,2,2-trifluoroethyl group, making it a valuable intermediate in medicinal chemistry, agrochemical synthesis, and materials science. Its unique trifluoroethyl moiety enhances electrophilicity and metabolic stability, ideal for probing structure-activity relationships (SAR) or developing fluorinated bioactive molecules. Packaged under inert conditions to ensure stability, this product is rigorously tested via HPLC, NMR, and mass spectrometry to meet ≥95% purity standards. Suitable for use in cross-coupling reactions, sulfonylation protocols, and as a building block for heterocyclic scaffolds.

Properties

  • CAS Number: 2326993-78-4
  • Complexity: 282
  • IUPAC Name: N-(2,2,2-trifluoroethyl)thiophene-2-sulfonamide
  • InChI: InChI=1S/C6H6F3NO2S2/c7-6(8,9)4-10-14(11,12)5-2-1-3-13-5/h1-3,10H,4H2
  • InChI Key: RQJPNEOMLOOPPG-UHFFFAOYSA-N
  • Exact Mass: 244.97920527
  • Molecular Formula: C6H6F3NO2S2
  • Molecular Weight: 245.2
  • SMILES: C1=CSC(=C1)S(=O)(=O)NCC(F)(F)F
  • Topological: 82.8
  • Monoisotopic Mass: 244.97920527
  • Synonyms: N-(2,2,2-Trifluoroethyl)thiophene-2-sulfonamide, 2326993-78-4, AKOS039322324

Application

N-(2,2,2-Trifluoroethyl)thiophene-2-sulfonamide serves as a key synthon in pharmaceutical research, particularly for designing enzyme inhibitors or fluorinated drug candidates due to its sulfonamide pharmacophore. It is also employed in agrochemical development to enhance pesticidal activity via fluorine incorporation. Additionally, its thiophene ring enables applications in conductive polymer research and ligand design for catalysis.

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

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Certain molecules may be protected by active patents or regulatory restrictions.

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  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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