Description

Methyl Glycolate (CAS No. 96-35-5), with the molecular formula C₃H₆O₃ and IUPAC name methyl 2-hydroxyacetate, is a high-purity ester of glycolic acid, widely utilized in organic synthesis and specialty chemical applications. This colorless to pale yellow liquid exhibits excellent solvency properties and is valued for its reactivity as a bifunctional compound, featuring both hydroxyl and ester functional groups. With a molecular weight of 90.08 g/mol and a boiling point of approximately 149-151°C, it is supplied in rigorously controlled batches to ensure consistency for research and industrial processes. Ideal for use as a precursor in pharmaceuticals, agrochemicals, and polymer modifications, our Methyl Glycolate is packaged under inert conditions to maintain stability and purity (>98% by GC). Available in quantities from grams to bulk orders, each shipment includes comprehensive analytical documentation (GC/MS, NMR) to meet stringent quality requirements.

Properties

• CAS Number: 96-35-5
• Complexity: 50
• IUPAC Name: methyl 2-hydroxyacetate
• InChI: InChI=1S/C3H6O3/c1-6-3(5)2-4/h4H,2H2,1H3
• InChI Key: GSJFXBNYJCXDGI-UHFFFAOYSA-N
• Exact Mass: 90.031694049
• Molecular Formula: C3H6O3
• Molecular Weight: 90.08
• SMILES: COC(=O)CO
• Topological: 46.5
• Monoisotopic Mass: 90.031694049
• Physical Description: Clear light yellow liquid;
• Synonyms: Methyl glycolate, methyl 2-hydroxyacetate, Methyl hydroxyacetate, Acetic acid, hydroxy-, methyl ester, Glycolic acid, methyl ester, Hydroxyacetic Acid Methyl Ester, Acetic acid, 2-hydroxy-, methyl ester, Methyl 2-hydroxyethanoate, EINECS 202-502-7, 7G7R729EJ0, NSC 27786, NSC-27786, UNII-7G7R729EJ0, DTXSID3059131, Methyl ester of hydroxyacetic acid, DTXCID4048981, Acetic acid, hydroxy, methyl ester, Glycolic acid, methyl ester (8CI), Acetic acid, 2hydroxy, methyl ester, gsjfxbnyjcxdgi-uhfffaoysa-n, inchi=1/c3h6o3/c1-6-3(5)2-4/h4h,2h2,1h, 96-35-5, 2-hydroxyacetic acid methyl ester, MFCD00004667, Glycolic Acid Methyl Ester, methyl2-hydroxyacetate, methyl2-hydroxyethanoate, Methyl glycolate, 98%, oxyacetic acid methyl ester, SCHEMBL21453, SCHEMBL23365, SCHEMBL596379, SCHEMBL1387681, SCHEMBL4302988, hydroxy-acetic acid methyl ester, SCHEMBL16196651, NSC27786, STR00937, BBL009725, STL141090, AKOS005716966, CS-W004068, FM32897, SB83763, BP-13422, SY003097, DB-001049, G0199, NS00020244, EN300-42324, Q27894348, F0001-2294, 124238-96-6

Application

Methyl Glycolate serves as a versatile intermediate in organic synthesis, particularly in the production of fine chemicals and active pharmaceutical ingredients (APIs) where its hydroxyl and ester groups enable esterification and transesterification reactions. It is employed as a building block for biodegradable polymers and surfactants due to its hydrolyzable ester linkage. In agrochemical formulations, it acts as a solvent or co-solvent for active ingredients requiring enhanced penetration. Researchers also utilize it in catalytic studies for green chemistry applications, leveraging its renewable derivability from glycolic acid.

Safety and Hazards

GHS Hazard Statements

• H227 (33.3%): Combustible liquid [Warning Flammable liquids]
• H315 (83.3%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (83.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (83.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P210, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403, P403+P233, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 4 (33.3%)
• Skin Irrit. 2 (83.3%)
• Eye Irrit. 2 (83.3%)
• STOT SE 3 (83.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.