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Atomfair Methyl 6-(bromomethyl)-3-fluoropicolinate C8H7BrFNO2

Description Methyl 6-(bromomethyl)-3-fluoropicolinate (CAS No. 1256836-16-4) is a high-purity, specialized chemical compound with the molecular formula C8H7BrFNO2. This fluorinated picolinate derivative is an essential building block in organic synthesis and pharmaceutical research, particularly for the development of novel heterocyclic compounds. The presence of both bromomethyl and fluorine substituents on the pyridine ring enhances its reactivity, making it a valuable intermediate for cross-coupling reactions, nucleophilic substitutions, and medicinal chemistry applications. Each batch is rigorously analyzed by HPLC, GC-MS, and NMR to ensure ??98% purity, meeting the stringent requirements of research and industrial laboratories. Available in convenient quantities (100mg to 10g) with…

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Description

Description

Methyl 6-(bromomethyl)-3-fluoropicolinate (CAS No. 1256836-16-4) is a high-purity, specialized chemical compound with the molecular formula C8H7BrFNO2. This fluorinated picolinate derivative is an essential building block in organic synthesis and pharmaceutical research, particularly for the development of novel heterocyclic compounds. The presence of both bromomethyl and fluorine substituents on the pyridine ring enhances its reactivity, making it a valuable intermediate for cross-coupling reactions, nucleophilic substitutions, and medicinal chemistry applications. Each batch is rigorously analyzed by HPLC, GC-MS, and NMR to ensure ??98% purity, meeting the stringent requirements of research and industrial laboratories. Available in convenient quantities (100mg to 10g) with optional custom packaging under inert atmosphere for stability-sensitive applications.

  • CAS No: 1256836-16-4
  • Molecular Formula: C8H7BrFNO2
  • Molecular Weight: 248.05
  • Exact Mass: 246.96442
  • Monoisotopic Mass: 246.96442
  • IUPAC Name: methyl 6-(bromomethyl)-3-fluoropyridine-2-carboxylate
  • SMILES: COC(=O)C1=C(C=CC(=N1)CBr)F
  • Synonyms: Methyl 6-(bromomethyl)-3-fluoropicolinate, 1256836-16-4, methyl 6-(bromomethyl)-3-fluoropyridine-2-carboxylate, DB-172421, F73614

Application

Methyl 6-(bromomethyl)-3-fluoropicolinate serves as a key intermediate in the synthesis of fluorinated pharmaceutical candidates, particularly kinase inhibitors and CNS-active compounds. Its reactive bromomethyl group facilitates facile functionalization for structure-activity relationship (SAR) studies in drug discovery. The compound is also utilized in material science for creating fluorinated ligands in catalytic systems. Researchers employ it as a precursor for radiolabeling experiments due to the favorable leaving group properties of the bromine substituent.

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