Description
Methyl 4-Chloropicolinate (CAS No. 24484-93-3) is a high-purity chemical compound with the molecular formula C7H6ClNO2. This versatile intermediate is widely used in pharmaceutical research, agrochemical synthesis, and organic chemistry applications. As a chlorinated picolinate ester, it offers unique reactivity for heterocyclic transformations and serves as a key building block for more complex molecular structures. Our product is rigorously tested to ensure ≥98% purity by HPLC analysis, with batch-specific certificates of analysis available. Supplied in amber glass bottles under inert atmosphere to ensure stability, this compound is ideal for demanding synthetic applications where consistent quality is critical.
Key specifications include: molecular weight 171.58 g/mol, melting point 35-38°C, and boiling point 260-262°C. The compound is soluble in common organic solvents including methanol, ethanol, DCM, and DMF. Special handling is recommended due to potential sensitization effects – always use appropriate PPE in well-ventilated areas. Storage at 2-8°C under nitrogen is recommended for long-term stability.
Properties
- CAS Number: 24484-93-3
- Complexity: 151
- IUPAC Name: methyl 4-chloropyridine-2-carboxylate
- InChI: InChI=1S/C7H6ClNO2/c1-11-7(10)6-4-5(8)2-3-9-6/h2-4H,1H3
- InChI Key: VTENWIPSWAMPKI-UHFFFAOYSA-N
- Exact Mass: 171.0087061
- Molecular Formula: C7H6ClNO2
- Molecular Weight: 171.58
- SMILES: COC(=O)C1=NC=CC(=C1)Cl
- Topological: 39.2
- Monoisotopic Mass: 171.0087061
- Synonyms: Methyl 4-Chloropicolinate, 24484-93-3, DTXSID20356253, DTXCID30307312, 677-529-4, methyl 4-chloropyridine-2-carboxylate, 4-Chloro-pyridine-2-carboxylic acid methyl ester, 2-PYRIDINECARBOXYLIC ACID, 4-CHLORO-, METHYL ESTER, methyl 4-chloro-2-pyridinecarboxylate, 4-Chloropyridine-2-carboxylic acid methyl ester, 4-Chloropicolinic Acid Methyl Ester, 4-Chloro-2-pyridinecarboxylic Acid Methyl Ester, MFCD04116183, Methyl4-chloropicolinate, methyl 4-chloro-pyridine-2-carboxylate, SS4GRT8SQE, 4-Chloro-pyridine-2-carboxylicacidmethylester, SCHEMBL177762, SCHEMBL4927916, VTENWIPSWAMPKI-UHFFFAOYSA-N, BCP26732, BBL104432, CL0195, GEO-00791, SBB053796, STL558661, METHYL 4-CHLORO-2-PICOLINATE, AKOS000265064, AB20667, AC-2888, CS-W008964, Picolinic acid, 4-chloro-, methyl ester, SY003263, DB-007680, M1832, ST50813735, EN300-24311, 4-Chloro-pyridine-2-carboxylic acid methylester, 4X-0703, AQ-405/42300546, F2108-0101, 4-Chloro-pyridine-2-carboxylic acid methyl ester, AldrichCPR
Methyl 4-Chloropicolinate serves as a crucial intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Researchers utilize this compound for palladium-catalyzed cross-coupling reactions to create diverse pyridine derivatives. In agrochemical research, it finds application as a precursor for novel pesticide development. The chloropyridine moiety makes it valuable for structure-activity relationship studies in medicinal chemistry programs.
Safety and Hazards
GHS Hazard Statements
- H315 (97%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (93.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (97%)
- Eye Irrit. 2 (100%)
- STOT SE 3 (93.9%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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