Atomfair

Awaiting product image

Atomfair Methyl 2-(4-methylphenyl)-2-oxoacetate C10H10O3 CAS 34966-53-5

Methyl 2-(4-methylphenyl)-2-oxoacetate (CAS No. 34966-53-5) is a high-purity organic compound with the molecular formula C10H10O3. This ester derivative, also known as methyl 4-methylbenzoylformate, is a versatile building block in synthetic organic chemistry, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its structure features a reactive α-ketoester moiety adjacent to a para-methylphenyl group, making it a valuable intermediate for nucleophilic additions, condensations, and cyclization reactions. The compound is supplied as a clear to pale-yellow liquid or low-melting solid with ≥95% purity (GC), ensuring consistent performance in research and industrial applications. Proper storage under inert atmosphere and refrigeration is recommended…

Category:

Description

Methyl 2-(4-methylphenyl)-2-oxoacetate (CAS No. 34966-53-5) is a high-purity organic compound with the molecular formula C10H10O3. This ester derivative, also known as methyl 4-methylbenzoylformate, is a versatile building block in synthetic organic chemistry, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its structure features a reactive α-ketoester moiety adjacent to a para-methylphenyl group, making it a valuable intermediate for nucleophilic additions, condensations, and cyclization reactions. The compound is supplied as a clear to pale-yellow liquid or low-melting solid with ≥95% purity (GC), ensuring consistent performance in research and industrial applications. Proper storage under inert atmosphere and refrigeration is recommended to maintain stability.

Properties

  • CAS Number: 34966-53-5
  • Complexity: 202
  • IUPAC Name: methyl 2-oxo-2-(p-tolyl)acetate
  • InChI: InChI=1S/C10H10O3/c1-7-3-5-8(6-4-7)9(11)10(12)13-2/h3-6H,1-2H3
  • InChI Key: IGFZBRICJIHTBI-UHFFFAOYSA-N
  • Exact Mass: 178.062994177
  • Molecular Formula: C10H10O3
  • Molecular Weight: 178.18
  • SMILES: CC1=CC=C(C=C1)C(=O)C(=O)OC
  • Topological: 43.4
  • Monoisotopic Mass: 178.062994177
  • Synonyms: 34966-53-5, methyl 2-(4-methylphenyl)-2-oxoacetate, Methyl 2-oxo-2-(p-tolyl)acetate, Methyl 4-methylbenzoylformate, methyl 2-oxo-2-p-tolylacetate, SCHEMBL3757531, Methyl2-oxo-2-(p-tolyl)acetate, JBA96653, methyl (4-methylphenyl)(oxo)acetate, AKOS006230472, DB-334498, CS-0237258, EN300-181023, G22933

Application

Methyl 2-(4-methylphenyl)-2-oxoacetate serves as a key precursor in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs). Researchers utilize this compound in Knoevenagel condensations to access α,β-unsaturated carbonyl derivatives with potential biological activity. It also finds application in material science as a monomer for specialty polymers. The para-methyl substitution pattern enhances its utility in directed ortho-metalation reactions for selective functionalization.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products