Atomfair Methyl 2-(4-methylphenyl)-2-oxoacetate C10H10O3

Description Methyl 2-(4-methylphenyl)-2-oxoacetate (CAS No. 34966-53-5) is a high-purity organic compound with the molecular formula C10H10O3. This ester derivative, also known as methyl 4-methylbenzoylformate, is a versatile building block in synthetic organic chemistry, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its structure features a reactive ??-ketoester moiety adjacent to a para-methylphenyl group, making it a valuable intermediate for nucleophilic additions, condensations, and cyclization reactions. The compound is supplied as a clear to pale-yellow liquid or low-melting solid with ??95% purity (GC), ensuring consistent performance in research and industrial applications. Proper storage under inert atmosphere and refrigeration is…

Description

Methyl 2-(4-methylphenyl)-2-oxoacetate (CAS No. 34966-53-5) is a high-purity organic compound with the molecular formula C₁₀H₁₀O₃. This ester derivative, also known as methyl 4-methylbenzoylformate, is a versatile building block in synthetic organic chemistry, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its structure features a reactive ??-ketoester moiety adjacent to a para-methylphenyl group, making it a valuable intermediate for nucleophilic additions, condensations, and cyclization reactions. The compound is supplied as a clear to pale-yellow liquid or low-melting solid with ??95% purity (GC), ensuring consistent performance in research and industrial applications. Proper storage under inert atmosphere and refrigeration is recommended to maintain stability.

CAS No: 34966-53-5
Molecular Formula: C10H10O3
Molecular Weight: 178.18
Exact Mass: 178.062994177
Monoisotopic Mass: 178.062994177
IUPAC Name: methyl 2-(4-methylphenyl)-2-oxoacetate
SMILES: CC1=CC=C(C=C1)C(=O)C(=O)OC
Synonyms: 34966-53-5, methyl 2-(4-methylphenyl)-2-oxoacetate, Methyl 2-oxo-2-(p-tolyl)acetate, Methyl 4-methylbenzoylformate, methyl 2-oxo-2-p-tolylacetate

Application

Methyl 2-(4-methylphenyl)-2-oxoacetate serves as a key precursor in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs). Researchers utilize this compound in Knoevenagel condensations to access ??,??-unsaturated carbonyl derivatives with potential biological activity. It also finds application in material science as a monomer for specialty polymers. The para-methyl substitution pattern enhances its utility in directed ortho-metalation reactions for selective functionalization.

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