Description

Description

Methyl 2-(3-aminophenyl)acetate hydrochloride (CAS No. 150319-83-8) is a high-purity organic compound with the molecular formula C₉H₁₂ClNO₂. This hydrochloride salt derivative of methyl 3-aminophenylacetate is a valuable intermediate in pharmaceutical and biochemical research. The compound features a benzene ring substituted with an amino group at the meta position and an ester-functionalized acetic acid side chain, protonated as a hydrochloride salt for enhanced stability.

With a molecular weight of 201.65 g/mol, this white to off-white crystalline powder is ideal for synthetic applications requiring precise control over aromatic amine reactivity. The hydrochloride form improves solubility in polar solvents while maintaining the reactivity of the aromatic amine group. Our product is rigorously tested to ensure ??95% purity by HPLC, with detailed analytical data (NMR, MS) available upon request.

Packaged under inert atmosphere in amber glass vials to prevent degradation, this chemical is suitable for use as:

• Key intermediate in active pharmaceutical ingredient (API) synthesis
• Building block for heterocyclic compound preparation
• Precursor for functional materials research

Application

Methyl 2-(3-aminophenyl)acetate hydrochloride serves as a versatile intermediate in medicinal chemistry, particularly in the synthesis of non-steroidal anti-inflammatory drug candidates. The compound’s aromatic amine functionality allows for diverse derivatization through diazotization, acylation, or coupling reactions. Researchers utilize this material in developing novel benzodiazepine analogs and other CNS-active compounds. The ester group provides a handle for further transformation to carboxylic acid derivatives or amide formation.

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