Description

(Methoxymethyl)(methyl)diphenylsilane (CAS No. 18407-48-2) is a high-purity organosilicon compound with the molecular formula C₁₅H₁₈OSi. This versatile reagent is widely used in organic synthesis, particularly in the protection of alcohols and the preparation of silicon-based intermediates. Its unique structure, featuring both methoxymethyl and methyl groups attached to a diphenylsilane backbone, makes it an excellent choice for selective transformations in complex molecular architectures. The product is rigorously tested to ensure ≥98% purity (GC), making it suitable for demanding applications in pharmaceutical research, material science, and specialty chemical synthesis. Supplied in amber glass bottles under inert atmosphere to guarantee stability and shelf life.

Properties

• CAS Number: 18407-48-2
• Complexity: 199
• IUPAC Name: methoxymethyl-methyl-diphenyl-silane
• InChI: InChI=1S/C15H18OSi/c1-16-13-17(2,14-9-5-3-6-10-14)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3
• InChI Key: ZOYKQGYFQVOLQH-UHFFFAOYSA-N
• Exact Mass: 242.112691728
• Molecular Formula: C15H18OSi
• Molecular Weight: 242.39
• SMILES: COC[Si](C)(C1=CC=CC=C1)C2=CC=CC=C2
• Topological: 9.2
• Monoisotopic Mass: 242.112691728
• Synonyms: (Methoxymethyl)(methyl)diphenylsilane, 18407-48-2

(Methoxymethyl)(methyl)diphenylsilane serves as a key protecting group reagent for hydroxyl functionalities in multistep syntheses. It demonstrates exceptional stability under basic conditions while remaining cleavable under mild acidic treatment. The compound finds particular utility in nucleoside and carbohydrate chemistry where selective protection is required. Researchers also employ it as a precursor for silicon-containing polymers with tailored thermal and mechanical properties.

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