Description

Idra-21 (CAS No. 22503-72-6) is a high-purity benzothiadiazine derivative with the molecular formula C₈H₉ClN₂O₂S. Its IUPAC name is 7-chloro-3-methyl-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine 1,1-dioxide. This compound is widely recognized in neuroscience research for its potent activity as an ampakine, modulating AMPA-type glutamate receptors to enhance synaptic transmission. Available in various quantities, our Idra-21 is rigorously tested for purity and stability, ensuring reliable performance in experimental applications. Suitable for in vitro and in vivo studies, it is an essential tool for researchers investigating cognitive enhancement, neuroprotection, and synaptic plasticity mechanisms.

Properties

• CAS Number: 22503-72-6
• Complexity: 314
• IUPAC Name: 7-chloro-3-methyl-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine 1,1-dioxide
• InChI: InChI=1S/C8H9ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-5,10-11H,1H3
• InChI Key: VZRNTCHTJRLTMU-UHFFFAOYSA-N
• Exact Mass: 232.0073264
• Molecular Formula: C8H9ClN2O2S
• Molecular Weight: 232.69
• SMILES: CC1NC2=C(C=C(C=C2)Cl)S(=O)(=O)N1
• Topological: 66.6
• Monoisotopic Mass: 232.0073264
• Synonyms: 22503-72-6, Idra-21, idra 21, 7-Chloro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide, 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, 7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, 689UW7PT68, IDRA21, 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide, 2H-1,2,4-Benzothiadiazine, 7-chloro-3,4-dihydro-3-methyl-, 1,1-dioxide, 7-chloro-3-methyl-3,4-dihydro-2H-1^{6},2,4-benzothiadiazine-1,1-dione, 7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-BENZO(E)(1,2,4)THIADIAZINE 1,1-DIOXIDE, 7-chloro-3-methyl-3,4-dihydro-2H-1^(6),2,4-benzothiadiazine-1,1-dione, 839-213-6, 163936-78-5, 163936-79-6, MFCD00270874, 7-chloro-3-methyl-3-4-dihydro-2h-1,2,4 benzothiadiazine s,s-dioxide, 7-chloro-3-methyl-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine 1,1-dioxide, 7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-Dioxide;, (+)-IDRA-21, (-)-IDRA-21, Biomol-NT_000225, CHEMBL77862, SCHEMBL195328, UNII-689UW7PT68, BPBio1_001088, GTPL4219, DTXSID70936887, EX-A737, CHEBI:111162, GLXC-06833, HMS3267D13, HMS3412O19, HMS3676O19, BCP19065, 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide, HB0334, s2434, AKOS024456473, IDRA 21, >=98%, 2H-1,2,4-Benzothiadiazine, 7-chloro-3,4-dihydro-3-methyl-, 1,1-dioxide, (+)-, 2H-1,2,4-Benzothiadiazine, 7-chloro-3,4-dihydro-3-methyl-, 1,1-dioxide, (-)-, NCGC00025050-02, DA-49967, DS-11824, SY105342, HY-101528, CS-0021632, ST50825828, SR-01000597374, Q5970086, SR-01000597374-1, BRD-A14344385-001-01-6, BRD-A14344385-001-02-4, BRD-A14344385-001-03-2, S 18986;S18986;IDRA-21;IDRA21;IDRA 21;AMPAKINE, 7-chloro-3-methyl-3H-benzo[e]1,2,4-thiadiazaperhydroine-1,1-dione, 7-Chloro-3-methyl-3,4-dihydro-1lambda6,2,4-benzothiadiazine-1,1(2H)-dione, (+)-, 7-chloro-3-methyl-3,4-dihydro-2H-1^{6,2,4-benzothiadiazine 1,1-dioxide

Application

Idra-21 is primarily used in neuroscience research as a positive allosteric modulator of AMPA receptors, enhancing excitatory synaptic transmission. It has shown promise in studies focused on cognitive enhancement, neuroprotection, and memory formation. Researchers also utilize Idra-21 to investigate synaptic plasticity and neurodegenerative disease models.

Safety and Hazards

GHS Hazard Statements

• Not Classified
• Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website.

Hazard Classes and Categories

• Not Classified

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.