Description

Ido-IN-1 (CAS 914638-30-5) is a high-purity small molecule inhibitor with the molecular formula C₉H₇BrFN₅O₂. This compound, also known as 4-amino-N’-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide, is a potent and selective inhibitor of indoleamine 2,3-dioxygenase (IDO), an enzyme implicated in immune regulation and tumor immune evasion. With a well-characterized structure and >98% purity (HPLC), Ido-IN-1 is ideal for in vitro and in vivo research applications in immunology and oncology. Each batch undergoes rigorous QC validation (NMR, LC-MS) to ensure consistency for pharmacological studies. Available in milligram to gram quantities with custom packaging options.

Properties

• CAS Number: 914638-30-5
• Complexity: 321
• IUPAC Name: 4-amino-N’-(3-bromo-4-fluoro-phenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboxamidine
• InChI: InChI=1S/C9H7BrFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)
• InChI Key: ORHZJUSHZUCMKR-UHFFFAOYSA-N
• Exact Mass: 314.97672
• Molecular Formula: C9H7BrFN5O2
• Molecular Weight: 316.09
• SMILES: C1=CC(=C(C=C1N=C(C2=NON=C2N)NO)Br)F
• Topological: 110
• Monoisotopic Mass: 314.97672
• Synonyms: IDO-IN-1, 914638-30-5, 4-Amino-N-(3-bromo-4-fluorophenyl)-N’-hydroxy-1,2,5-oxadiazole-3-carboximidamide, (Z)-4-amino-N-(3-bromo-4-fluorophenyl)-N’-hydroxy-1,2,5-oxadiazole-3-carboximidamide, CHEMBL565923, 4-amino-N’-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide, (4E)-4-[(3-bromo-4-fluoroanilino)-nitrosomethylidene]-1,2,5-oxadiazol-3-amine, IDO-IN1, MFCD28399146, C9H7BrFN5O2, IDO-IN-5L, IDO-IN-1?, SCHEMBL149915, SCHEMBL149916, SCHEMBL149917, SCHEMBL16706552, SCHEMBL20585913, ORHZJUSHZUCMKR-UHFFFAOYSA-N, GLXC-90422, BCP16681, EX-A2317, BDBM50300306, s6728, AKOS027338387, AKOS032960406, AB89561, CS-4599, AC-33925, AS-52505, HY-79531, P15269, (E)-4-Amino-N’-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide, (z)-4-amino-N-(3-bromo-4-fluorophenyl)-N’-hydroxy-1,2,5-oxadiazole-3-carboximid amide, 4-amino-N-(3-bromo-4-fluoro-phenyl)-N’-hydroxy-1,2,5-oxadiazole-3-carboxamidine, 4-Amino-N-(3-bromo-4-fluorophenyl)-N”-hydroxy-1,2,5-oxadiazole-3-carboximidamide

Application

Ido-IN-1 is widely used in immunological and cancer research to study the role of IDO in immune suppression and tumor microenvironment modulation. It serves as a valuable tool compound for validating IDO as a therapeutic target in autoimmune diseases and immuno-oncology. Researchers utilize this inhibitor to investigate T-cell suppression mechanisms and enhance the efficacy of checkpoint inhibitor therapies.

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.